Disease & disorder

juvenile idiopathic arthritis

MONDO:0011429

Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases).

Clinical trials46
Recruiting3
Drug concepts studied15
Synonyms9

Disease research snapshot

CureCurrent currently links 46 distinct registered clinical trials to juvenile idiopathic arthritis through its MONDO disease mappings. 3 of those studies have the registry status “recruiting” (7%). These are registry statuses, not availability guarantees, study results or evidence of effectiveness.

The leading sponsor shown in this linked dataset is Amgen, associated with 4 distinct linked trials. This is a count of records, not a ranking of the sponsor's scientific quality.

The highest-count mapped research city in the current result is Cincinnati, United States. Only site locations available in the published registry projection are counted; some trial sites may be missing or outdated.

The most frequently mapped drug concept in the current linked trials is etanercept (4 distinct trials). This describes what has been studied, not a recommended treatment.

Numbers are derived from CureCurrent's current ClinicalTrials.gov projection and conservative MONDO/RxNorm mappings. See sources, counting rules and limitations and verify eligibility or clinical findings with the original study record.

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Recruiting studies by city

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Trial status

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Investigated drug interventions

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Clinical trials

40 shown
Pain in Inflammatory Joint DiseasesNCT06718569 · 2025-11-11
RECRUITING
Health and Exercise Response in Children With Chronic and Auto-immune PathologiesNCT03913962 · 2019-05-02
RECRUITING
Medical Follow-up of New Cases of Polyarthritis in Children and Young AdultsNCT07000916 · 2013-09-11
RECRUITING
Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With ArthritisNCT04585711 · 2026-07-01
WITHDRAWN
Mesenchymal Stem Cells Infusion in Patients With Autoimmune DiseasesNCT06888973 · 2025-02-01
ENROLLING_BY_INVITATION
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic DiseasesNCT05879419 · 2023-05-23
ACTIVE_NOT_RECRUITING
Rheumatology-based Adaptive Intervention for Social Determinants and Health EquityNCT05715463 · 2023-03-01
ACTIVE_NOT_RECRUITING
Transition to Adulthood Through Coaching and Empowerment in RheumatologyNCT05545839 · 2022-10-17
COMPLETED
Effect of Electroacupuncture on Refractory Pain in Juvenile Rheumatoid Arthritis: Randomized Controlled TrialNCT05504382 · 2022-08-01
UNKNOWN
Host-microbiota-environment InteractionsNCT05176795 · 2022-03-16
TERMINATED
Effectiveness and Feasibility of a Home-based Exercise Program for Adolescents With Juvenile Idiopathic ArthritisNCT05114343 · 2021-12-01
UNKNOWN
Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and InflammationNCT04902807 · 2021-09-07
COMPLETED
Genicular Nerve Block in Juvenile Idiopathic ArthritisNCT04687930 · 2020-12-01
COMPLETED
Denosumab for Glucocorticoid-treated Children With Rheumatic DisordersNCT02418273 · 2019-08-01
WITHDRAWN
Yellow Fever Vaccine in Patients With Rheumatic DiseasesNCT03430388 · 2018-01-31
COMPLETED
Treatment Tapering in JIA With Inactive DiseaseNCT02840175 · 2017-05-18
COMPLETED
Start Time Optimization of Biologics in Polyarticular JIANCT02593006 · 2015-11-01
COMPLETED
PatientSpot Formerly Known as ArthritisPowerNCT03840928 · 2015-04-01
UNKNOWN
Anti-Biopharmaceutical Immunization: Prediction and Analysis of Clinical Relevance to Minimize the Risk of Immunization in Rheumatoid Arthritis Patients or Juvenile Idiopathic Arthritis PatientsNCT02116504 · 2014-04-01
UNKNOWN
Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFαNCT01694264 · 2012-09-01
TERMINATED
Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic DiseasesNCT01151644 · 2010-04-01
UNKNOWN
Use of Thermal and 3D Imaging to Quantify ArthritisNCT01044823 · 2010-01-01
COMPLETED
Safety and Effectiveness of Rilonacept for Treating Systemic Juvenile Idiopathic Arthritis in Children and Young AdultsNCT00534495 · 2008-11-01
COMPLETED
Safety, Efficacy, and Pharmacokinetics of Adalimumab in Japanese Children With Juvenile Rheumatoid ArthritisNCT00690573 · 2008-05-01
COMPLETED
Growth Hormone in Children With Juvenile Rheumatoid Arthritis (JRA) and With Crohn's DiseaseNCT00511329 · 2007-08-01
TERMINATED
Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic ArthritisNCT00443430 · 2007-05-01
COMPLETED
Effects of Growth Hormone in Chronically Ill ChildrenNCT00286689 · 2006-02-03
WITHDRAWN
BMS-188667 in Children and Adolescents With Juvenile Rheumatoid ArthritisNCT00095173 · 2003-12-01
COMPLETED
PEAK Study (Physical Exercise and Activity in Kids)NCT00213187 · 2002-08-01
COMPLETED
Infliximab to Treat Children With Juvenile Rheumatoid ArthritisNCT00029042 · 2002-01-01
TERMINATED
Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid ArthritisNCT00078806 · 2001-06-04
TERMINATED
Randomized Fixed Bearing vs Mobile Bearing Cruciate Substituting TKANCT00289107 · 2001-04-01
COMPLETED
Randomized Fixed Bearing vs Mobile Bearing Cruciate Retaining TKANCT00289094 · 2001-03-01
COMPLETED
Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune DisordersNCT00010335 · 2000-11-01
COMPLETED
Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid ArthritisNCT03781375 · 2000-08-24
TERMINATED
Registry of Etanercept (Enbrel®) In Children With Juvenile Rheumatoid ArthritisNCT00078793 · 2000-06-01
COMPLETED
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune DiseasesNCT00006055 · 2000-03-01
UNKNOWN
Retrospective Analysis of Pulmonary Arterial Hypertension (PAH) and Related Complications in Juvenile Idiopathic Arthritis (JIA) Participants Treated With Biologic and Non-biologic Disease-modifying Anti-rheumatic Drugs (DMARDs)NCT02784808 · 2000-01-01
COMPLETED
TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid ArthritisNCT00001862 · 1999-02-01
COMPLETED
The Safety and Efficacy of Chicken Type II Collagen on Uveitis Associated With Juvenile Rheumatoid ArthritisNCT00001614 · 1997-07-01
COMPLETED

How to interpret this record

CureCurrent links normalized diseases, medicines, registry study labels, sponsors and research sites. A link is not the same as a finding of clinical effectiveness. Our research guides explain how to compare studies, decode RxNorm identities, and avoid over-interpreting site and trial counts. See the published database coverage for mapping completeness.

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.