Disease & disorder

low compliance bladder

MONDO:0001446

Clinical trials0
Recruiting0
Drug concepts studied0
Synonyms2

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

Loading mapped interventions…

MONDO disease family

Loading verified ontology relationships…

Recruiting studies by city

Loading research-site locations…

Trial status

Loading…

Trial phase

Loading…

Study start year

Loading…

Investigated drug interventions

Loading…
Background context

Overactive bladder

Overactive bladder (OAB) is a common condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life. Overactive bladder is characterized by a group of four symptoms: urgency, urinary frequency, nocturia, and urge incontinence. Urinary frequency is defined as urinating more than about 7-8 times in one day. The frequent need to urinate may occur during the day, at night, or both. The number of episodes varies depending on sleep, fluid intake, medications, and up to seven is considered normal if consistent with the other factors. In addition, patients with OAB experience urinary urgency, a sudden feeling that they have to get to the bathroom very quickly. Lastly, they may experience nocturia, which is waking up at night to urinate. Loss of bladder control (urge incontinence) is a form of urinary incontinence characterized by the involuntary loss of urine occurring for no apparent reason while feeling urinary urgency as discussed above, and often occurs with this condition. This condition is also sometimes characterized by a sudden and involuntary contraction of the bladder muscles, in response to excitement or anticipation. OAB is distinct from stress urinary incontinence (SUI), but when they occur together, the condition is usually known as mixed urinary incontinence. Treatment of mixed urinary incontinence usually focuses on the more bothersome component between OAB and SUI. Overactive bladder affects approximately 11% of the population and more than 40% of people with overactive bladder have incontinence. Converse...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.