Disease & disorder

Madras motor neuron disease

MONDO:0015307

Madras motor neuron disease (MMND) is characterized by weakness and atrophy of limbs, multiple lower cranial nerve palsies and sensorineural hearing loss.

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Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Background context

Madras motor neuron disease

Madras motor neuron disease is a rare motor neuron disease originating in South India. Two other forms of the disease have been found, Familial Madras Motor Neuron Disease (FMMND) and the variant Madras Motor Neuron Disease (MMNDV). The symptoms of MMND include weakness in the arms and legs, loss of vision, and deafness. Most affected individuals are diagnosed by the age of 15 and occurs at the same frequency in males and females. While the cause of the disease and its origins are not yet known, supportive care is available to individuals affected by the disease.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.