Disease & disorder

malignant epithelioid mesothelioma

MONDO:0005599

A malignant neoplasm arising from mesothelial cells in the pleura. It is characterized by the presence of neoplastic cells with an epithelioid appearance. In the majority of cases, the neoplastic epithelioid cells lack significant cytologic atypia; mitotic figures are infrequently seen. In a minority of cases, the neoplastic cells are poorly differentiated and there is evidence of nuclear atypia and increased mitotic activity.

Clinical trials13
Recruiting0
Drug concepts studied8
Synonyms5

Disease research snapshot

CureCurrent currently links 13 distinct registered clinical trials to malignant epithelioid mesothelioma through its MONDO disease mappings. 0 of those studies have the registry status “recruiting” (0%). These are registry statuses, not availability guarantees, study results or evidence of effectiveness.

The leading sponsor shown in this linked dataset is National Cancer Institute (NCI), associated with 11 distinct linked trials. This is a count of records, not a ranking of the sponsor's scientific quality.

The highest-count mapped research city in the current result is Chicago, United States. Only site locations available in the published registry projection are counted; some trial sites may be missing or outdated.

The most frequently mapped drug concept in the current linked trials is cisplatin (4 distinct trials). This describes what has been studied, not a recommended treatment.

Numbers are derived from CureCurrent's current ClinicalTrials.gov projection and conservative MONDO/RxNorm mappings. See sources, counting rules and limitations and verify eligibility or clinical findings with the original study record.

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Recruiting studies by city

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Trial status

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Trial phase

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Study start year

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Investigated drug interventions

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Background context

malignant epithelioid mesothelioma

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

13 shown
Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant MesotheliomaNCT03228537 · 2018-07-16
ACTIVE_NOT_RECRUITING
Pembrolizumab in Treating Patients With Malignant MesotheliomaNCT02399371 · 2015-03-31
COMPLETED
Tivantinib in Treating Patients With Previously Treated Malignant MesotheliomaNCT01861301 · 2013-01-01
TERMINATED
AMG 102, Pemetrexed Disodium, and Cisplatin in Treating Patients With Malignant Pleural MesotheliomaNCT01105390 · 2010-04-01
WITHDRAWN
Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural MesotheliomaNCT01064648 · 2010-03-15
ACTIVE_NOT_RECRUITING
Study of Safety and Tolerability of Intravenous CRS-207 in Adults With Selected Advanced Solid Tumors Who Have Failed or Who Are Not Candidates for Standard TreatmentNCT00585845 · 2007-12-01
TERMINATED
PXD101 as Second-Line Therapy in Treating Patients With Malignant Mesothelioma of the Chest That Cannot Be Removed By SurgeryNCT00365053 · 2006-06-01
COMPLETED
Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By SurgeryNCT00309946 · 2005-12-01
COMPLETED
S0509 - AZD2171 in Treating Patients With Malignant Pleural Mesothelioma That Cannot Be Removed By SurgeryNCT00243074 · 2005-11-01
COMPLETED
Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma.NCT00107432 · 2004-10-01
COMPLETED
Erlotinib in Treating Patients With Malignant Mesothelioma of the LungNCT00039182 · 2002-05-01
COMPLETED
Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant MesotheliomaNCT00027703 · 2001-10-01
COMPLETED
Gefitinib in Treating Patients With Malignant MesotheliomaNCT00025207 · 2001-09-01
COMPLETED

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.