Disease & disorder

narcissistic personality disorder

MONDO:0002411

A disorder characterized by an enduring pattern of grandiose beliefs and arrogant behavior together with an overwhelming need for admiration and a lack of empathy for (and even exploitation of) others.

Clinical trials1
Recruiting0
Drug concepts studied0
Synonyms0

Disease research snapshot

CureCurrent currently links 1 distinct registered clinical trials to narcissistic personality disorder through its MONDO disease mappings. 0 of those studies have the registry status “recruiting” (0%). These are registry statuses, not availability guarantees, study results or evidence of effectiveness.

The leading sponsor shown in this linked dataset is Daniel Serrani Azcurra, associated with 1 distinct linked trials. This is a count of records, not a ranking of the sponsor's scientific quality.

Numbers are derived from CureCurrent's current ClinicalTrials.gov projection and conservative MONDO/RxNorm mappings. See sources, counting rules and limitations and verify eligibility or clinical findings with the original study record.

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Recruiting studies by city

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Trial status

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Investigated drug interventions

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Background context

Narcissistic personality disorder

Narcissistic personality disorder (NPD) is a complex and heterogeneous personality disorder characterized by patterns of grandiosity, entitlement, low empathy, and interpersonal difficulties, which can manifest as either grandiose ("thick-skinned") or vulnerable ("thin-skinned") forms. Grandiose individuals display arrogance, social dominance, and exploitative behaviors, while vulnerable individuals show shame, inferiority, hypersensitivity, and extreme reactions to criticism. NPD often involves impaired emotional empathy, superficial relationships, and difficulty tolerating disagreement. It is often co-morbid with other mental disorders and associated with significant functional impairment and psychosocial disability. There are two definitions of NPD in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM); whereas the primary definition is categorical and stems from previous DSM editions, the other definition – part of the Alternative DSM-5 model for personality disorders – is based on dimensional measures of severity of the disorder as well as on specific pathological traits. The International Classification of Diseases (ICD) defines only a general personality disorder since the introduction of the latest edition; hence, it does not include an NPD category. There is no standard treatment for NPD. Its high comorbidity with other mental disorders influences treatment and outcomes. Psychotherapeutic treatments generally fall into two categories: psychoanalytic/psychodynamic and cognitive behavioral therapy, with growing suppor...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.