Disease & disorder

obsolete MONDO:0004915

MONDO:0004915

Clinical trials0
Recruiting0
Drug concepts studied0
Synonyms0

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Recruiting studies by city

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Trial status

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Background context

Periodontosis

Periodontosis is an obsolete term that was used to describe what was once thought to be certain type of unique and distinguishable chronic periodontal disease that manifested as degenerative bony changes without concomitant inflammation. Although utilized for more than 50 years, the term has since been dropped in favor of a more contemporary disease classification for periodontal disease. Described by Gottlieb as a "diffuse atrophy of the alveolar bone," the term periodontosis was later applied and it gained acceptance as a disease entity, being defined as: "a degenerative, noninflammatory destruction of the periodontium, originating in one or more of the periodontal structures and characterized by migrating and loosening of the teeth in the presence or absence of secondary epithelial proliferation and pocket formation or secondary gingival disease." Noted as a rare disease, periodontosis was said to have been seen primarily in young patients. And despite being defined as being a "noninflammatory destruction of the periodontium," almost all cases did exhibit varying degrees of gingival inflammation.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.