Disease & disorder

pinnae fistula or cyst

MONDO:0015477

A rare otorhinolaryngological disease characterized by the presence of a, usually unilateral, sinus tract or cyst located in the vicinity of the auricle (most frequently identified by a small pit near the anterior margin of the first ascending portion of the helix). Typically, patients are asymptomatic and usually only present symptoms (pain, erythema, discharge from pit) in relation to infection. Renal and inner ear anomalies may be associated.

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Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Preauricular sinus and cyst

Preauricular sinuses, also known as preauricular pits and preauricular cysts, are common malformations present at birth that involve the external ear. A cyst does not connect with the skin, while a sinus does. Both ears are often affected. They may be associated with other defects such as branchio-oto-renal syndrome. They are often inherited from a persons parents. They affect about 0.1–0.9% of people in the US, 0.9% in the UK, and 4–10% in Asia and parts of Africa.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.