pleural empyema
MONDO:0018667
The presence of pus in the thoracic cavity, between the visceral and parietal pleura.
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Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
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Pleural empyema
Pleural empyema is a collection of pus in the pleural cavity. It is caused by microorganisms, usually bacteria. It often happens in the context of a pneumonia, injury, or chest surgery. It is one of the various kinds of pleural effusion. Pleural empyema contains three stages: exudative: when there is an increase in pleural fluid with or without the presence of pus; fibrinopurulent: when fibrous septa form localized pus pockets, and the final organizing stage: when there is scarring of the pleura membranes with possible inability of the lung to expand. Simple pleural effusions occur in up to 40% of bacterial pneumonias. They are usually small and resolve with appropriate antibiotic therapy. However, if an empyema develops additional intervention is required.
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.