progestogen hypersensitivity
MONDO:0021952
Progestogen hypersensitivity (PH), also referred to as autoimmune progesterone dermatitis (APD), is a rare immediate or delayed hypersensitivity reaction to endogenous progesterone and/or synthetic progestins characterized by diverse cutaneous manifestations, bronchospasm, and/or anaphylaxis.
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Autoimmune progesterone dermatitis
Autoimmune progesterone dermatitis (APD) occurs during the luteal phase of a woman's menstrual cycle and is an uncommon cyclic premenstrual reaction to progesterone. It can present itself in several ways, including eczema, erythema multiforme, urticaria, angioedema, and progesterone-induced anaphylaxis. The first case of autoimmune progesterone dermatitis was identified in 1964. Reproductive function may be impacted by APD.
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Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.