reading seizures
MONDO:0007560
A rare reflex epilepsy characterized by reading-induced seizures which in most cases present with orofacial/jaw myoclonus possibly extending to the upper limbs but can also manifest as dyslexia or alexia and visual symptoms. In both variants secondary generalized tonic-clonic seizures may evolve if the stimulus is not interrupted. The disease typically begins in the second or third decade of life and may be inherited in an autosomal dominant pattern. It usually takes a benign course with little tendency to spontaneous seizures.
Research intelligence
Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
Medications under investigation
Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
MONDO disease family
Recruiting studies by city
Trial status
Trial phase
Study start year
Investigated drug interventions
Reading epilepsy
Reading epilepsy is a type of a reflex seizure caused by reading. Reading epilepsy is one of a number of reflex seizures. The reflex seizures are characterized by epileptic seizures occurring due to reflex, i.e. caused by a specific stimulus, contrary to other epilepsy types with spontaneous seizures. In discussed case reading becomes a trigger, as loud reading as a quiet one. In effect seizure can occur, including oral area myoclonus, especially affecting masseter muscle, orbicularis oris muscle, oral and perioral myoclonus. Extremities can be affected too. Apart from that, affected person can be unable to read. EEG performed during the seizure complexes of sharp waves and slow waves from a dominant hemisphere, especially from a temporoparietal area, can be observed. However, between the seizures no electroencephalographic changes can be detected. There is no lesion observable in the head MRI either. Reading epilepsy occurs more frequently in boys aged from 12 to 20 years. A genetic base is suspected. In the case of reading epilepsy a change of reading manner is recommended as a prevention. Koutroumanidis et al. (1998) described a case series, in which they administered anticolvulsive medicines. The seizure disappeared in 9 patients of 14. Clonazepam was proved effective drug when valproic acid did not act in some patients.
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.