Disease & disorder

seborrheic dermatitis

MONDO:0006608

A chronic, inflammatory skin disorder that affects the scalp, central face and skin folds; it is characterized by scaling and itching.

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Synonyms6

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Seborrhoeic dermatitis

Seborrhoeic dermatitis or seborrheic dermatitis (depending upon the variety of English used) is a long-term skin disorder. Symptoms include flaky, scaly, greasy, and occasionally itchy and inflamed skin. Areas of the skin rich in oil-producing glands are often affected including the scalp, face, and chest. It can result in social or self-esteem problems. In babies, when the scalp is primarily involved, it is called cradle cap. Mild seborrhoeic dermatitis of the scalp may be described in lay terms as dandruff due to the dry, flaky character of the skin. As dandruff may refer to any dryness or scaling of the scalp, not all dandruff is seborrhoeic dermatitis. Seborrhoeic dermatitis is sometimes inaccurately referred to as seborrhoea. The cause is unclear but believed to involve a number of genetic and environmental factors. Risk factors for seborrhoeic dermatitis include poor immune function, Parkinson's disease, and alcoholic pancreatitis. The condition may worsen with stress or during the winter. Malassezia yeast is believed to play a role. It is not a result of poor hygiene. Diagnosis is typically clinical and based on the symptoms present. The condition is not contagious. The typical treatment is topical antifungal cream and anti-inflammatory agents. Specifically, ketoconazole or ciclopirox are effective. Seborrhoeic dermatitis of the scalp is often treated with shampoo preparations of ketoconazole, zinc pyrithione, piroctone olamine and selenium disulfide. Gentle, non-irritating cleansers and moisturizers are often used alongside medicated treatments to maintain the sk...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.