Disease & disorder

seborrheic keratosis

MONDO:0008420

A common benign skin neoplasm usually affecting older individuals. The lesions usually are multiple and arise in the face, chest, and shoulders. They appear as black or brown, slightly elevated skin lesions.

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Synonyms3

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Seborrheic keratosis

A seborrheic keratosis is a non-cancerous (benign) skin tumor that originates from cells, namely keratinocytes, in the outer layer of the skin called the epidermis. Like liver spots, seborrheic keratoses are seen more often as people age. The tumors (also called lesions) appear in various colors, from light tan to black. They are round or oval, feel flat or slightly elevated, like the scab from a healing wound, and range in size from very small to more than 2.5 centimetres (1 in) across. They are often associated with other skin conditions, including basal cell carcinoma. Sometimes, seborrheic keratosis and basal cell carcinoma occur at the same location. At clinical examination, a differential diagnosis considers warts and melanomas. Because only the top layers of the epidermis are involved, seborrheic keratoses are often described as having a "pasted-on" appearance. Some dermatologists refer to seborrheic keratoses as "seborrheic warts", because they resemble warts, but strictly speaking, the term "warts" refers to lesions that are caused by the human papillomavirus.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.