Disease & disorder

stutter disorder

MONDO:0000723

A speech disorder characterized by frequent sound or syllable repetitions, sound prolongations, or other dysfluencies that are inappropriate for the individual's age.

Clinical trials0
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Synonyms3

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Stuttering

Stuttering, also known as stammering, is a speech disorder characterized externally by involuntary repetitions and prolongations of sounds, syllables, words, or phrases as well as involuntary silent pauses called blocks in which the person who stutters is unable to produce sounds. Almost 80 million people worldwide stutter, about 1% of the world's population, with a prevalence among males at least twice that of females. Persistent stuttering into adulthood often leads to outcomes detrimental to overall mental health, such as social isolation and suicidal thoughts. Stuttering is not connected to the physical ability to produce phonemes (i.e. it is unrelated to the structure or function of the vocal cords). It is also unconnected to the structuring of thoughts into coherent sentences inside sufferers' brains, meaning that people with a stutter know precisely what they are trying to say (in contrast with alternative disorders like aphasia). Stuttering is purely a neurological disconnect between intent and outcome during the task of expressing each individual sound. While there are rarer neurogenic (e.g. acquired during physical insult) and psychogenic (e.g. acquired after adult-onset mental illness or trauma) variants, the typical etiology, development, and presentation is that of idiopathic stuttering in childhood that then becomes persistent into adulthood. Acute nervousness and stress do not cause stuttering but may trigger increased stuttering in people who have the disorder. There is a significant correlation between anxiety, particularly social anxiety, and stuttering...

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Drugs being studied

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.