substance abuse
MONDO:0002491
The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed.
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Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
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Substance abuse
Substance use, also known as drug use or, in older vernacular, substance abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a health issue. It is a form of substance-related disorder. Differing definitions of drug misuse are used in public health, medical, and criminal justice contexts. In some cases, criminal or anti-social behavior occurs when some persons are under the influence of a drug, and may result in long-term personality changes in individuals. In addition to possible physical, social, and psychological harm, the use of some drugs may also lead to criminal penalties, although these vary widely depending on the local jurisdiction. Drugs most often associated with this term include alcohol, amphetamines, barbiturates, benzodiazepines, cannabis, cocaine, hallucinogens, methaqualone, and opioids. The exact cause of substance abuse is sometimes unclear, but there are two predominant theories: either a genetic predisposition or a habit learned or passed down from others, which, if addiction develops, manifests itself as a possible chronic debilitating disease. It is not easy to determine why a person misuses drugs, as there are multiple environmental factors to consider. These factors include not only inherited biological influences (genes), but there are also mental health stressors such as overall quality of life, physical or mental abuse, luck and circumstance in life, and early exposure to drugs, all play a significant role in how people will respond to drug use. In 2010, about 5% of adults (230 million) used...
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Clinical trials
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Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.