Disease & disorder
univentricular heart
MONDO:0015451
Univentricular heart (UVH) is a severe congenital cardiac malformation characterized by both atria related entirely or almost entirely to one functionally single ventricular chamber. The clinical manifestations include congestive heart failure, failure to thrive, cyanosis, hypoxemia and neurodevelopmental disabilities.
Research intelligence
Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
Medications under investigation
Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
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Background context
univentricular heart
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Clinical trials
5 shownCardiac Magnetic Resonance Stress-perfusion Study in Patinets with Fontan CirculationNCT06735521 · 2024-04-15
RECRUITINGAutologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart DiseaseNCT05647213 · 2023-02-03
RECRUITINGRegistry to Assess the Safety and Feasibility of the Subpulmonary Support with the Novel Venous Cannula in Patients with Failing/Absence of the Right HeartNCT04782232 · 2021-06-01
RECRUITINGOcclutech AFR Fontan StudyNCT07532369 · 2026-05-01
NOT_YET_RECRUITINGEfficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart DiseaseNCT03997097 · 2023-06-01
WITHDRAWNDrugs being studied
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Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.