Drug & intervention
ofatumumab
RxCUI 712566
RxNorm ingredient and formulation relationships
Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.
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Clinical trials
26 shownExploring the Efficacy and Safety of Ofatumumab in Patients With Relapsing Multiple Sclerosis (RMS) and Its Impact on Serum Neurofilament Light Chain (sNfL) LevelsNCT07353216 · 2023-12-01
RECRUITINGSwitch to Ofatumumab and Level of ImmunoglobulinsNCT07625800 · 2026-06-01
NOT_YET_RECRUITINGAn Open-Label, Single-Arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of CD20 Monoclonal Antibody Combined With NK042 Cell Injection in the Treatment of Multiple Sclerosis (MS).NCT07546110 · 2026-05-01
NOT_YET_RECRUITINGITAKOS - Italian Observation, Multicenter, Prospective Study of Ofatumumab in RRMS PatientsNCT06345157 · 2024-07-30
ACTIVE_NOT_RECRUITINGWOE of Anti-CD20 TherapiesNCT06121349 · 2023-12-04
COMPLETEDRetinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking OfatumumabNCT06167642 · 2023-05-22
ENROLLING_BY_INVITATIONEffects of Ofatumumab Treatment on Immune Cells and Meningeal Lymphatic Drainage in Patients With Demyelinating DiseasesNCT05414487 · 2022-10-15
UNKNOWNA Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) ElevationNCT05090371 · 2022-03-02
ACTIVE_NOT_RECRUITINGReduced Oligodendrocyte-specific Cytotoxicity and Ofatumumab TreatmentNCT05171972 · 2022-01-29
COMPLETEDStudy to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.NCT05084638 · 2022-01-25
COMPLETEDEfficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple SclerosisNCT04926818 · 2021-10-05
ACTIVE_NOT_RECRUITINGOpen Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMSNCT04788615 · 2021-07-23
COMPLETEDA Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With OfatumumabNCT04878211 · 2021-06-10
TERMINATEDExploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With OfatumumabNCT04869358 · 2021-05-27
COMPLETEDTime and Motion Study for Ocrelizumab and Ofatumumab Administration in Relapsing Multiple SclerosisNCT04676555 · 2021-05-11
COMPLETEDA Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With OfatumumabNCT04667117 · 2021-01-14
COMPLETEDA Single Arm Study Evaluating the Efficacy, Safety and Tolerability of Ofatumumab in Patients With Relapsing Multiple SclerosisNCT04486716 · 2020-10-19
COMPLETED9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple SclerosisNCT04510220 · 2020-09-21
COMPLETEDEfficacy and Safety of Ofatumumab Compared to Placebo in Patients With Relapsing Multiple Sclerosis Followed by Extended Treatment With Open-label OfatumumabNCT03249714 · 2018-03-15
COMPLETEDA Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic LeukemiaNCT01578707 · 2012-06-01
COMPLETEDOfatumumab vs Physician's Choice in Subjects With Bulky Fludarabine-Refractory Chronic Lymphocytic LeukemiaNCT01313689 · 2011-04-14
COMPLETEDOfatumumab in Japanese Patients With CD20 Positive Follicular Lymphoma or Chronic Lymphocytic LeukemiaNCT00742144 · 2008-09-19
COMPLETEDStudy to Evaluate SC Route of Administration of Ofatumumab in RA PatientsNCT00686868 · 2008-06-13
COMPLETEDInvestigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to TNF-α Antagonist TherapyNCT00603525 · 2008-01-01
TERMINATEDInvestigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to MTX TherapyNCT00611455 · 2008-01-01
TERMINATEDLong-term Efficacy and Safety of Repeated Ofatumumab Treatment Courses in RA Patients Who Previously Received Ofatumumab or Placebo in Trial Hx-CD20-403NCT00655824 · 2008-01-01
TERMINATEDConditions being studied
Multiple Sclerosis7Relapsing Multiple Sclerosis5Arthritis, Rheumatoid4Demyelinating Diseases of the Central Nervous System1Leukaemia1Leukaemia, Lymphocytic, Chronic and Lymphoma, Follicular1Multiple Sclerosis (MS)1Multiple Sclerosis, Relapsing-Remitting1Neuromyelitis Optica Spectrum Disorder1Relapse Remitting Multiple Sclerosis1Relapsed or Refractory Chronic Lymphocytic Leukemia1Relapsing Forms of Multiple Sclerosis1Relapsing Multiple Sclerosis (RMS)1Relapsing Remitting Multiple Sclerosis1Relapsing-Remitting Multiple Sclerosis1Retinal Degeneration1Small Lymphocytic Lymphoma1Tomography, Optical Coherence1Visual Acuity1
Research locations
Los AngelesCalifornia, United States5PhoenixArizona, United States5MadridSpain4SevilleSpain4TampaFlorida, United States4BostonMassachusetts, United States3Clermont-FerrandFrance3DetroitMichigan, United States3HollywoodFlorida, United States3HoustonTexas, United States3KnoxvilleTennessee, United States3LodzPoland3
Leading sponsors
Novartis Pharmaceuticals13GlaxoSmithKline5Brigham and Women's Hospital1Johns Hopkins University1Pharmacyclics LLC.1The Affiliated Hospital of Xuzhou Medical University1Third Affiliated Hospital, Sun Yat-Sen University1Tianjin Medical University General Hospital1University Hospital, Lille1University of Southern California1
Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.