Intervention

Hydrochlorothiazide

ClinicalTrials.gov intervention label

Clinical trials75

Recruiting1

Common conditions25

Lead sponsors shown15

Clinical trials

60 shown

Bariatric Surgery and Pharmacokinetics of HydrochlorothiazideNCT03476551 · 2016-11-02

Multi-Omics to Predict the Blood Pressure Response to AntihypertensivesNCT05917275 · 2024-04-04

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channel Blockers Versus HydrochlorothiazideNCT05125224 · 2021-10-01

Sympathetic Regulation of Large Artery Stiffness in Humans With ISHNCT04423627 · 2021-06-01

Hydrochlorothiazide and Risk of Skin CancerNCT04334824 · 2019-05-27

Protocol of Diuretics Use in Congestive Therapy in Heart FailureNCT03892148 · 2019-05-17

N-of-1 Trials In Children With HypertensionNCT03461003 · 2018-04-02

A Drug to Drug Interaction Study of Sotagliflozin With HydrochlorothiazideNCT03387657 · 2018-01-03

Anxiety-mediated Impairments in Large Elastic Artery Function and the Autonomic Nervous SystemNCT03109795 · 2017-04-10

EBMtrialcentral- Comparing Initial Diuretic Therapies Using a Collaborative NetworkNCT01748123 · 2016-08-01

Peripheral Vascular Effects of Sulfhydryl-containing Antihypertensive Pharmacotherapy on Microvessels in HumansNCT03179163 · 2016-07-20

Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With HypertensionNCT02646397 · 2016-02-01

Aliskiren Study of Safety and Efficacy in Senior HypertensivesNCT01922141 · 2015-05-01

RAS Peptide Profiles in Patients With Arterial HypertensionNCT02449811 · 2015-04-01

Treatment of OSA Associated Hypertension With Alpha 2 Agonist or DiureticNCT02699125 · 2015-01-01

Treatment of OSA Associated Hypertension With Nebivolol or HydrochlorothiazideNCT02710071 · 2015-01-01

A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/HydrochlorothiazideNCT02222480 · 2014-10-01

Telmisartan and Hydrochlorothiazide Antihypertensive Treatment Study in High Sodium Intake PopulationNCT02255253 · 2014-10-01

INTERVENCION TrialNCT02373163 · 2014-09-01

N-of-1 Trials for Blood Pressure Medications in AdultsNCT02744456 · 2014-08-01

Treatment of Hypertension in Tibetan Adult PopulationNCT02217852 · 2014-08-01

Vascular Dysfunction in Human Obesity HypertensionNCT01983462 · 2013-10-01

Series of N-of-1 Crossover Trials of Antihypertensive Therapy in Adolescents With Essential HypertensionNCT02412761 · 2013-06-01

Study to Evaluate the Efficacy and Safety of Combined Administration of TAK-536CCB and Hydrochlorothiazide in Patients With Grade I or II Essential Hypertension.NCT02072330 · 2013-03-01

A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for HypertensionNCT01658657 · 2012-10-01

Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance ArteriesNCT01480791 · 2012-01-01

Effect of Aliskiren and Hydrochlorothiazide on Kidney Oxygenation in Patients With HypertensionNCT01519635 · 2011-10-01

Safety and Tolerability of Valsartan in Children 6 to 17 Years of AgeNCT01365481 · 2011-08-01

Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and LisinoprilNCT01258764 · 2010-11-01

Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal InsufficiencyNCT01172431 · 2010-09-01

Treatment of Adiposity Related hypErTension (TARGET)NCT01138423 · 2010-08-01

Telmisartan, Amlodipine and Flow Mediated DilationNCT01180205 · 2010-08-01

Effects of Dapagliflozin on Kidney Function (Glomerular Filtration Rate) in Subjects With Type 2 DiabetesNCT00976495 · 2009-10-01

Study to Determine the Effects of Nebivolol and Hydrochlorothiazide in African Americans With HypertensionNCT00999752 · 2009-10-01

Evaluating the Effect of Aliskiren Versus HCTZ on Coronary Flow Reserve in Hypertensive Type II DiabeticsNCT00994253 · 2009-08-01

Telmisartan 80mg Plus Hydrochlorothiazide 25mg First Line in Moderate or Severe HypertensionNCT00926289 · 2009-06-01

A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male VolunteersNCT00923533 · 2009-03-01

Aliskiren Plus HCTZ Compared to Aliskiren in Metabolic Syndrome Patients With Stage 2 Systolic HypertensionNCT00797316 · 2008-11-01

Blood Pressure Lowering of Aliskiren HCTZ Compared to HCTZ in Stage 2 Systolic Hypertension in Older PopulationNCT00760266 · 2008-09-01

Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate HypertensionNCT00765947 · 2008-09-01

A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential HypertensionNCT00667719 · 2008-06-05

18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 DiabeticsNCT00654745 · 2008-05-01

Safety and Efficacy Study of a Triple Combination Therapy in Subjects With HypertensionNCT00649389 · 2008-05-01

A Comparison of Indapamide SR 1.5 mg With HCTZ 25 mg, in Combination With an ACE-inhibitor, in Patients With Mild to Moderate AHT and Type 2 DMNCT00980187 · 2008-03-01

Candesartan Effect in Second Stage Arterial HypertensionNCT00621153 · 2008-02-01

Efficacy of Irbesartan/Hydrochlorothiazide Versus Valsartan/Hydrochlorothiazide in Mild to Moderate HypertensionNCT00500604 · 2007-07-01

Efficacy and Safety of Valsartan and Amlodipine (± HCTZ) in Adults With Moderate, Inadequately Controlled HypertensionNCT00523744 · 2007-07-01

Metabolic Effects of Antihypertensive Drugs on People With Metabolic Syndrome (The MEAD Study)NCT00887510 · 2007-05-01

Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular HypertrophyNCT00446563 · 2007-03-01

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and PlaceboNCT00434967 · 2007-01-01

An Assessment of Long Term Safety of the Combination of Aliskiren / Amlodipine in Patients With High Blood PressureNCT00402103 · 2006-11-01

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/12.5 and 32/25 mg in Comparison With Candesartan 32 mgNCT00383929 · 2006-09-01

A Study in People With Mild HypertensionNCT00374855 · 2006-09-01

A Safety and Efficacy Trial of Aliskiren 150mg , 300 mg Compared to Ramipril 5mg, 10mg in the ElderlyNCT00368277 · 2006-09-01

Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management StrategyNCT00935805 · 2006-07-01

A Study of VAH631 in Patients With Essential Hypertension (Factorial Study)NCT00311740 · 2006-03-01

Irbesartan in the Treatment of Hypertensive Patients With Metabolic SyndromeNCT00110422 · 2005-11-01

Pharmacogenomic Evaluation of Antihypertensive ResponsesNCT00246519 · 2005-10-01

Black Education and Treatment of Hypertension (BEAT HTN)NCT00661895 · 2005-08-01

Reducing the Overall Risk Level in Patients Suffering From Metabolic SyndromeNCT00821574 · 2005-07-01

Common conditions

Leading sponsors

Novartis10 AstraZeneca5 Boehringer Ingelheim5 Daiichi Sankyo3 Novartis Pharmaceuticals3 Boryung Pharmaceutical Co., Ltd2 Brigham and Women's Hospital2 Sanofi2 The University of Texas Health Science Center, Houston2 University of California, San Diego2 University of Florida2 University of Iowa2 West China Hospital2 Anna Posadzy-Małaczyńska1 Bristol-Myers Squibb1

Trial status mix

COMPLETED62

UNKNOWN5

WITHDRAWN4

TERMINATED3

RECRUITING1

Phase mix

PHASE434

PHASE315

PHASE29

NA7

PHASE14

EARLY_PHASE12

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.