Intervention

Poly ICLC

ClinicalTrials.gov intervention label

Clinical trials10
Recruiting3
Common conditions25
Lead sponsors shown8

Clinical trials

10 shown
Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual DiseaseNCT06529822 · 2025-03-20
RECRUITING
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung CancerNCT05098210 · 2022-06-09
RECRUITING
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast CancerNCT03606967 · 2021-04-13
RECRUITING
Harnessing Allo-immunity to Enhance Immune Checkpoint Inhibitor Responses in Advanced NSCLCNCT06064279 · 2024-06-04
WITHDRAWN
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid TumorsNCT04616248 · 2023-01-09
ACTIVE_NOT_RECRUITING
Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid TumorsNCT04116320 · 2019-11-21
TERMINATED
Personalized Therapeutic Anti-tumor Vaccine With Pembrolizumab and Standard of Care Chemotherapy in Squamous Non-Small Cell Lung Cancer and Extensive Stage Small Cell Lung CancerNCT03166254 · 2019-04-30
WITHDRAWN
Vaccination With Flt3L, Radiation, and Poly-ICLCNCT03789097 · 2019-04-05
COMPLETED
Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant ChemotherapyNCT02427581 · 2015-09-29
WITHDRAWN
Development of Human Nasal Challenge Models With Microbial Constituents and Grass PollenNCT02090374 · 2014-03-01
COMPLETED

Common conditions

Anatomic Stage IV Breast Cancer AJCC v83Melanoma2Merkel Cell Carcinoma2Non Small Cell Lung Cancer2Non-small Cell Lung Cancer2Allergic Rhinitis1Asthma1Basal Cell Carcinoma1Bone Sarcoma1Breast Cancer1Cervical Cancer1Clinical Stage IV Cutaneous Melanoma AJCC v81Cutaneous Squamous Cell Carcinoma1Esophageal Cancer1Gastric Cancer1Gastroesophageal Adenocarcinoma1Head and Neck Squamous Cell Carcinoma1Hepatocellular Carcinoma1Invasive Breast Carcinoma1Latent Tuberculosis1Locally Advanced Cutaneous Melanoma1Locally Advanced Mucosal Melanoma1Metastatic Acral Melanoma1Metastatic Breast Cancer1Metastatic Breast Carcinoma1

Trial status mix

RECRUITING3
WITHDRAWN3
COMPLETED2
ACTIVE_NOT_RECRUITING1
TERMINATED1

Phase mix

PHASE18
PHASE23
NA1

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.