Intervention

Leflunomide

ClinicalTrials.gov intervention label

Clinical trials22
Recruiting4
Common conditions17
Lead sponsors shown15

Clinical trials

22 shown
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyNCT07138898 · 2025-12-12
RECRUITING
Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies and HER2 Negative Breast CancerNCT04997993 · 2023-12-13
RECRUITING
The Clinical Efficacy of Immunomodulators in RA PatientsNCT05626348 · 2021-12-22
RECRUITING
Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseNCT03414502 · 2007-12-10
RECRUITING
A Study of the Effectiveness of Additional Risk Minimization Measures Related to ARAVA® (Leflunomide) in Saudi ArabiaNCT06714461 · 2025-05-05
COMPLETED
Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS MutationsNCT06229340 · 2023-10-03
UNKNOWN
Leflunomide in Previously Treated Metastatic Triple Negative CancersNCT03709446 · 2019-04-16
COMPLETED
Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid ArthritisNCT03449758 · 2018-03-05
COMPLETED
Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate MonotherapyNCT02930343 · 2016-09-01
TERMINATED
Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid ArthritisNCT02644499 · 2015-12-31
COMPLETED
IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIANCT02451748 · 2015-08-01
COMPLETED
A Study Assessing the Safety and Efficacy of Sarilumab Added to Non-MTX DMARDs or as Monotherapy in Japanese Patients With Active Rheumatoid Arthritis (SARIL-RA-HARUKA)NCT02373202 · 2015-02-01
COMPLETED
To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid ArthritisNCT02057250 · 2014-03-01
COMPLETED
A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid ArthritisNCT01941095 · 2013-11-20
COMPLETED
Study of Iguratimod Plus Methotrexate Compared to Leflunomid Plus Methotrexate in Patients With Rheumatoid ArthritisNCT02275299 · 2013-09-01
UNKNOWN
Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging StudyNCT01659242 · 2012-07-01
TERMINATED
Effectiveness in Daily Practice of Different Treatment Strategies for Early Rheumatoid Arthritis.NCT01172639 · 2009-02-01
COMPLETED
A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Who Don't Have a Response to Anti-TNF-α Therapy (SCRIPT)NCT00476996 · 2007-05-15
TERMINATED
Effect of Leflunomide on T Cell Proliferation in HIV-Infected PatientsNCT00101374 · 2005-01-05
COMPLETED
Leflunomide in Rheumatoid ArthritisNCT00280644 · 2004-04-01
COMPLETED
Leflunomide + Methotrexate in Rheumatoid ArthritisNCT00563849 · 2003-05-01
COMPLETED
Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid ArthritisNCT00579878 · 2001-03-27
COMPLETED

Trial status mix

COMPLETED13
RECRUITING4
TERMINATED3
UNKNOWN2

Phase mix

PHASE49
PHASE37
PHASE13
PHASE23

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.