Intervention

Melatonin

ClinicalTrials.gov intervention label

How to interpret these research links

Connected source records

This is the original ClinicalTrials.gov intervention label, found in 45 distinct published trials. Registry interventions may represent drugs, devices, procedures or other study activities. A matched term or study association does not establish product equivalence, efficacy or regulatory approval.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials45
Recruiting3
Common conditions25
Lead sponsors shown15
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Clinical trials

45 shown
Effect of Melatonin in Patients With Diabetic Peripheral NeuropathyNCT07036796 · 2025-07-04
RECRUITING
Effect of Melatonin on Pulmonary Hypertension in Full Term NeonatesNCT07850934 · 2025-07-01
RECRUITING
Sleep, Diabetic Retinopathy and MelatoninNCT04547439 · 2021-02-03
RECRUITING
Melatonin for Glycemic Control in Gestational Diabetes MellitusNCT07369284 · 2026-02-01
NOT_YET_RECRUITING
Efficacy of Melatonin in the Treatment of Diabetic Nephropathy Compared With Folic AcidNCT07825961 · 2025-04-01
COMPLETED
Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive PatientsNCT06935292 · 2025-04-01
NOT_YET_RECRUITING
Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Disease SpectrumNCT06756828 · 2025-01-15
NOT_YET_RECRUITING
Effect of Melatonin on Schizophrenic Symptoms: a Randomized Placebo-Controlled TrialNCT06838104 · 2024-12-05
ACTIVE_NOT_RECRUITING
Melatonin for Pulmonary Hypertension in Full Term NeonatesNCT06685679 · 2024-05-15
COMPLETED
Melatonin in Obese Patients in Laparoscopic CholecystectomyNCT06355687 · 2024-04-01
UNKNOWN
Melatonin Effects on the Left Ventricular Function in Neonates With Persistent Pulmonary HypertensionNCT07090720 · 2023-01-01
COMPLETED
Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)NCT05319301 · 2022-04-01
COMPLETED
The Effect of Melatonin Supplementation on Fatigue Symptoms During Chemotherapy Treatment of Breast Cancer PatientsNCT06125353 · 2022-01-01
COMPLETED
Melatonin on Clock Genes in Parkinson's DiseaseNCT04287543 · 2021-05-01
WITHDRAWN
Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary SclerosisNCT03540485 · 2019-11-29
TERMINATED
Metabolic Effects of Melatonin TreatmentNCT03859934 · 2019-09-26
COMPLETED
Melatonin for Sleep in MSNCT04035889 · 2019-09-23
COMPLETED
Melatonin's Effects on Treatment Of Diabetes MellitusNCT02691897 · 2019-07-01
UNKNOWN
Melatonin Cream Against Acute Radiation Dermatitis in Patients With Early Breast CancerNCT03716583 · 2019-04-30
COMPLETED
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic HypotensionNCT02963181 · 2018-03-01
TERMINATED
Study MIPAE - Melatonin and Essential Arterial HypertensionNCT05257291 · 2018-02-02
UNKNOWN
Effect of Melatonin on Cardiometabolic Risk- FULLNCT02681887 · 2016-09-01
UNKNOWN
Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast CancerNCT02486796 · 2016-02-19
TERMINATED
The Effect of Melatonin on Early Signs of Hypertension in Teenagers With Diabetes Mellitus Type 1NCT02644590 · 2016-02-01
UNKNOWN
Effects of Melatonin Supplementation on Renal Physiology in a Habitual Sleep Restricted Population.NCT02631148 · 2016-01-01
TERMINATED
Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast CancerNCT02506790 · 2015-07-01
UNKNOWN
Melatonin for Nocturia in Parkinson's DiseaseNCT02359448 · 2015-04-01
UNKNOWN
Melatonin Supplementation for Cancer-related Fatigue in Patients Receiving RadiotherapyNCT02332928 · 2015-03-25
TERMINATED
Pharmacovigilance in Gerontopsychiatric PatientsNCT02374567 · 2015-01-01
TERMINATED
Anti-proliferative Effects of Vitamin D and Melatonin in Breast CancerNCT01965522 · 2013-10-01
COMPLETED
Melatonin and Glucose Tolerance Among Individuals With a Variant of the MTNR1B GeneNCT01705639 · 2012-11-01
COMPLETED
The Effect of Melatonin on Gene Expression and Activity of the Sirt1 and Its Target Genes Catalase and MnSOD in Multiple Sclerosis Patients and Healthy SubjectsNCT02463318 · 2012-09-01
COMPLETED
Effect of Melatonin on Multiple Sclerosis Related FatigueNCT01718678 · 2012-05-01
COMPLETED
Melatonin for Prevention of Metabolic Side Effects of OlanzapineNCT01593774 · 2012-05-01
COMPLETED
Melatonin as Adjuvant Therapy in Breast Cancer PatientsNCT01557478 · 2012-03-01
UNKNOWN
Melatonin Versus Placebo for Benzodiazepine Discontinuation in Patients With SchizophreniaNCT01431092 · 2011-10-01
COMPLETED
Melatonin in Relapsing-Remitting Multiple Sclerosis PatientsNCT01279876 · 2010-10-01
COMPLETED
Melatonin and Nighttime Blood Pressure in African Americans--24 mg StudyNCT01114373 · 2010-06-01
COMPLETED
Melatonin and Nighttime Blood Pressure in African Americans-8 mg StudyNCT01114360 · 2010-03-01
COMPLETED
Metabolic Effects of Melatonin in Patients Treated With Second Generation AntipsychoticsNCT01811160 · 2008-10-01
COMPLETED
Melatonin Treatment for Tardive Dyskinesia in SchizophreniaNCT01391390 · 2008-09-01
COMPLETED
Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer PatientsNCT00513357 · 2006-06-01
COMPLETED
Melatonin Supplements for Improving Sleep in Individuals With HypertensionNCT00238108 · 2005-10-01
COMPLETED
Melatonin Postoperative Sleep Study in Breast Cancer PatientsNCT00506064 · 2004-02-01
TERMINATED
Study of Melatonin: Sleep Problems in Alzheimer's DiseaseNCT00000171
COMPLETED

Common conditions

Hypertension5Breast Cancer4Melatonin3Schizophrenia3Alzheimer Disease2Diabetes Mellitus2Multiple Sclerosis2Obesity2Prediabetic State2Anesthesia1Anxiety Disorders1Autoimmune Diseases1Autoimmune Diseases of the Nervous System1Autonomic Nervous System Diseases1Biomarker with Neurodegeneration Patients1Bipolar Affective Disorder1Blood Pressure1Breast Cancer - Female1Central Diabetes Insipidus1Cerebellum1Cognitive Decline1Congenital Diaphragmatic Hernia1Congenital Peumonia1Dementia1Depression1

Leading sponsors

Ain Shams University 4 Brigham and Women's Hospital 3 Tanta University 3 Emory University 2 M.D. Anderson Cancer Center 2 Tehran University of Medical Sciences 2 Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 1 Beijing HuiLongGuan Hospital 1 Dennis Bregner Zetner 1 Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 1 Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 1 Guilan University of Medical Sciences 1 Hannover Medical School 1 Harokopio University 1 Instituto Mexicano del Seguro Social 1

Trial status mix

COMPLETED22
UNKNOWN8
TERMINATED7
NOT_YET_RECRUITING3
RECRUITING3
ACTIVE_NOT_RECRUITING1
WITHDRAWN1

Phase mix

PHASE220
NA11
PHASE310
PHASE14
EARLY_PHASE13
PHASE42
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.