Intervention
zoledronic acid
ClinicalTrials.gov intervention label
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov intervention label, found in 44 distinct published trials. Registry interventions may represent drugs, devices, procedures or other study activities. A matched term or study association does not establish product equivalence, efficacy or regulatory approval.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
44 shownBiomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic AcidNCT01409811 · 2012-09-14
TERMINATEDZoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal SymptomsNCT01194440 · 2011-02-01
COMPLETEDNeo-Adjuvant Chemotherapy (TAC) With or Without Zoledronic Acid in Treating HER2-negative Breast Cancer PatientsNCT01099436 · 2010-04-01
COMPLETEDZometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung CancerNCT01004510 · 2009-11-01
TERMINATEDExtended Endocrine Therapy for Premenopausal Women With Breast CancerNCT00903162 · 2009-05-01
COMPLETEDZoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone InvolvementNCT00869206 · 2009-03-01
COMPLETEDS0307A, Long-Term Bone Quality in Women With Breast Cancer Enrolled on Clinical Trial SWOG-S0307NCT00873808 · 2008-10-01
WITHDRAWNAndrogen Blockade Therapy With or Without Zoledronic Acid in Treating Patients With Prostate Cancer and Bone MetastasesNCT00685646 · 2008-05-01
COMPLETEDEvaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer PatientsNCT00912938 · 2007-12-01
UNKNOWNZoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast CancerNCT00365105 · 2006-07-11
COMPLETEDZANTE: Zometa and Taxotere in Hormone Refractory Prostate CancerNCT00415779 · 2006-07-01
COMPLETEDZoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast CancerNCT00436917 · 2006-04-01
COMPLETEDStudy of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate CancerNCT00321620 · 2006-04-01
COMPLETEDComparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the BoneNCT00458796 · 2006-03-01
TERMINATEDIbandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast CancerNCT00326820 · 2006-01-01
UNKNOWNAdoptive Immunotherapy, Aldesleukin, and Zoledronate in Treating Patients With Stage IV Kidney Cancer and Lung MetastasesNCT00588913 · 2006-01-01
COMPLETEDSafety and Efficacy Study of Concomitant Radiotherapy and Zoledronic Acid for Bone Metastases PalliationNCT00264420 · 2005-12-01
COMPLETEDEffectiveness of Zoledronic Acid in the Prevention of Osteoporosis in Early Breast Cancer Patients Receiving LetrozoleNCT00376740 · 2005-09-01
COMPLETEDS0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.NCT00127205 · 2005-07-01
COMPLETEDDocetaxel and Prednisolone With or Without Zoledronic Acid and/or Strontium Chloride Sr 89 in Treating Patients With Prostate Cancer Metastatic to Bone That Has Not Responded to Hormone TherapyNCT00554918 · 2005-02-01
COMPLETEDUsing TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung CancerNCT00265200 · 2005-02-01
TERMINATEDZoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast CancerNCT00107263 · 2005-01-01
COMPLETEDNon-small Cell Lung Cancer RegistryNCT00099541 · 2004-11-01
COMPLETEDThe Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting OsteoporosisNCT00171639 · 2004-06-01
COMPLETEDLetrozole With or Without Zoledronate in Treating Healthy Postmenopausal Women With High Breast DensityNCT00114270 · 2004-05-01
COMPLETEDNon-small Cell Lung Cancer Study US75 (Z-PACT)NCT00086268 · 2004-04-01
COMPLETEDHOBOE: A Phase 3 Study of Adjuvant Triptorelin and Tamoxifen, Letrozole, or Letrozole and Zoledronic Acid in Premenopausal Patients With Breast Cancer.NCT00412022 · 2004-03-01
UNKNOWNZoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone MetastasesNCT00079001 · 2004-01-01
COMPLETEDA Prostate Cancer Study in Men Undergoing Androgen Deprivation TherapyNCT00087659 · 2003-12-01
COMPLETEDAssessment of the Efficacy, Tolerability and Pharmaco-economic Impact of Zoledronic Acid Treatment in Prostate Cancer With Bone MetastasisNCT00241111 · 2003-09-01
COMPLETEDFrequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate CancerNCT00520052 · 2003-08-01
COMPLETEDChemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast CancerNCT00072020 · 2003-08-01
UNKNOWNThe Effect of Zoledronic Acid on Bone Loss in Prostate Cancer Patients Undergoing Androgen Deprivation TherapyNCT00063609 · 2003-04-01
COMPLETEDZoledronic Acid With Intermittent Hormonal Therapy in Patients With Prostate CancerNCT00226954 · 2003-03-01
TERMINATEDZolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen DeprivationNCT00058188 · 2003-03-01
TERMINATEDMonoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone MetastasesNCT00060138 · 2002-11-01
COMPLETEDZoledronate and BMS-275291 in Treating Patients With Prostate CancerNCT00039104 · 2002-04-01
COMPLETEDZoledronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy After Surgery For Early Stage Breast CancerNCT00049452 · 2001-12-01
COMPLETEDZoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast CancerNCT00022087 · 2001-12-01
COMPLETEDTreatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone LesionsNCT00029224 · 2001-10-01
COMPLETEDCalcitriol and Zoledronate in Treating Patients With Progressive Prostate CancerNCT00004928 · 1999-10-01
COMPLETEDZoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent Bone Metastases in Patients With Recurrent Prostate Cancer That Has No SymptomsNCT00005073 · 1999-09-01
TERMINATEDTamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic AcidNCT00295646 · 1999-06-01
COMPLETEDZoledronate in Treating Patients With Solid Tumors That Have Spread to the BoneNCT00003884 · 1998-08-01
COMPLETEDCommon conditions
Breast Cancer19Prostate Cancer12Metastatic Cancer10Osteoporosis7Pain5Hypercalcemia of Malignancy4Lung Cancer3Bone Metastases2Estrogen Receptor-positive Breast Cancer2Progesterone Receptor-positive Breast Cancer2Adenocarcinoma of the Prostate1Breast Adenocarcinoma1Carcinoma, Non-Small Cell Lung1Carcinoma, Small Cell Lung1DS Stage I Plasma Cell Myeloma1DS Stage II Plasma Cell Myeloma1Ductal Carcinoma in Situ1Invasive Ductal Breast Carcinoma1Kidney Cancer1Malignant Pleural Effusion1Metastases1Metastatic Breast Cancer1Metastatic Malignant Neoplasm to the Bone1Metastatic Prostate Cancer1Multiple Myeloma1
Leading sponsors
Novartis Pharmaceuticals
7
Alliance for Clinical Trials in Oncology
4
National Cancer Institute, Naples
2
Novartis
2
SWOG Cancer Research Network
2
Amgen
1
Austrian Breast & Colorectal Cancer Study Group
1
Borstkanker Onderzoek Groep
1
Chugai Pharmaceutical
1
City of Hope Medical Center
1
Dana-Farber Cancer Institute
1
Herbert Irving Comprehensive Cancer Center
1
Korean Breast Cancer Study Group
1
Mayo Clinic
1
Memorial Sloan Kettering Cancer Center
1
Trial status mix
COMPLETED32
TERMINATED7
UNKNOWN4
WITHDRAWN1
Phase mix
PHASE320
PHASE29
NA6
PHASE15
PHASE45
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.