Research location
Cape Town
Western Cape, South Africa
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Research activity in Cape Town
Western Cape, South AfricaCureCurrent currently publishes aggregate city-level research activity for this location: 314 trials and 449 site observations.
The map is centered on registry-derived city coordinates. Circle size reflects published trial activity.
Below are current trials with one or more ClinicalTrials.gov site observations in this city. Results are paginated 50 per page, with recruiting studies shown first.
Trials with sites in Cape Town
314 linked trials · page 1 of 7A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414 · 2026-05-21 · 1 site observation
RECRUITING
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and ObesityNCT07567001 · 2026-05-11 · 6 site observations
RECRUITING
Evaluation of Long-Acting Injectable (LAI) and Teen Clubs in Adolescents (ATTUNE).NCT06721078 · 2026-02-09 · 2 site observations
RECRUITING
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)NCT07216703 · 2026-01-19 · 1 site observation
RECRUITING
Universal Test and Connect for HIV Service Delivery in South AfricaNCT06408142 · 2026-01-19 · 1 site observation
RECRUITING
A Study to Evaluate Performance, Usability, and Contrived Result Interpretation of TruPlex HIV/HepB/Syphilis Rapid TestNCT07563309 · 2025-12-18 · 1 site observation
RECRUITING
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)NCT07276724 · 2025-12-03 · 2 site observations
RECRUITING
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple SclerosisNCT07225504 · 2025-11-11 · 1 site observation
RECRUITING
A Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-010)NCT07071623 · 2025-11-10 · 2 site observations
RECRUITING
Mentor Moms+ StudyNCT06962592 · 2025-09-01 · 1 site observation
RECRUITING
A Trial of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine, Administered to Healthy Adults Living Without and With HIV.NCT06617091 · 2025-07-28 · 1 site observation
RECRUITING
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)NCT06966700 · 2025-06-30 · 1 site observation
RECRUITING
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.NCT06846281 · 2025-06-23 · 1 site observation
RECRUITING
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South AfricaNCT05624931 · 2025-04-17 · 1 site observation
RECRUITING
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%NCT06561386 · 2024-10-07 · 1 site observation
RECRUITING
Post-Injectable Cabotegravir Antiretroviral Salvage Strategy Options TrialNCT06485154 · 2024-06-01 · 1 site observation
RECRUITING
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)NCT06312176 · 2024-04-14 · 1 site observation
RECRUITING
National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South AfricaNCT05982847 · 2024-04-01 · 3 site observations
RECRUITING
Evaluating the Safety and Immunogenicity of MTBVACNCT05947890 · 2024-01-30 · 3 site observations
RECRUITING
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)NCT06136650 · 2023-12-18 · 1 site observation
RECRUITING
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)NCT05714085 · 2023-05-31 · 2 site observations
RECRUITING
A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With AsthmaNCT05562466 · 2023-05-11 · 1 site observation
RECRUITING
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U MessagingNCT05602376 · 2023-03-31 · 1 site observation
RECRUITING
Remote Ischaemic Conditioning in STEMI Patients in AFRICANCT04813159 · 2022-01-12 · 3 site observations
RECRUITING
Pre- and Post-treatment Lung Microbiota, Metabolome and Immune Signatures at the Site of Disease in Patients With Active Pulmonary TuberculosisNCT04700579 · 2021-03-04 · 3 site observations
RECRUITING
Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Aged 4 Weeks to <12 Years and <45 kg (MK-1439-066)NCT04375800 · 2021-02-03 · 1 site observation
RECRUITING
Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South AfricaNCT05539989 · 2026-12-31 · 2 site observations
WITHDRAWN
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or ObesityNCT07861100 · 2026-10-26 · 2 site observations
NOT_YET_RECRUITING
Intervention Development for Syndemics Among PWH in SANCT06152003 · 2026-09-15 · 1 site observation
NOT_YET_RECRUITING
Khanya Ekhaya: A Home-Based InterventionNCT06985641 · 2026-08-17 · 1 site observation
ACTIVE_NOT_RECRUITING
Choice-Based Support for Adults Starting or Restarting Antiretroviral Therapy in Cape Town, South AfricaNCT07439562 · 2026-02-01 · 1 site observation
NOT_YET_RECRUITING
Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.NCT06694753 · 2025-12-15 · 2 site observations
ACTIVE_NOT_RECRUITING
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)NCT07044297 · 2025-07-31 · 1 site observation
ACTIVE_NOT_RECRUITING
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)NCT06966479 · 2025-05-21 · 1 site observation
ACTIVE_NOT_RECRUITING
Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy ParticipantsNCT05959707 · 2024-08-14 · 1 site observation
SUSPENDED
Phase III Long-Term Extension Study With DexpramipexoleNCT06388889 · 2024-06-12 · 1 site observation
TERMINATED
Pausing Antiretroviral Treatment Under Structured EvaluationNCT06031272 · 2024-05-28 · 1 site observation
COMPLETED
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminNCT06323161 · 2024-03-26 · 1 site observation
COMPLETED
A Study to Learn About the Vaccine RSVpreF In Pregnant Participants With HIV and Their InfantsNCT06325657 · 2024-03-12 · 2 site observations
COMPLETED
A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALIANT)NCT06196879 · 2024-02-27 · 1 site observation
COMPLETED
A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)NCT06269107 · 2024-02-15 · 1 site observation
COMPLETED
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06221969 · 2024-01-16 · 1 site observation
COMPLETED
A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11)NCT06099782 · 2023-12-26 · 2 site observations
ACTIVE_NOT_RECRUITING
Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)NCT06045507 · 2023-11-08 · 1 site observation
COMPLETED
A Randomized, Double-blind 2-arm, Followed by an Open-label 1-arm, NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.NCT05985915 · 2023-10-27 · 1 site observation
ACTIVE_NOT_RECRUITING
ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarENCT06248190 · 2023-09-19 · 16 site observations
COMPLETED
Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South AfricaNCT05944718 · 2023-09-11 · 2 site observations
COMPLETED
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South AfricaNCT05933226 · 2023-06-21 · 1 site observation
ACTIVE_NOT_RECRUITING
Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid ArthritisNCT05814627 · 2023-06-15 · 2 site observations
COMPLETED
A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and InflammationNCT05636176 · 2023-05-08 · 5 site observations
TERMINATED
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.