Research location
Johannesburg
South Africa
Research activity in Johannesburg
South AfricaCureCurrent currently publishes aggregate city-level research activity for this location: 384 trials and 490 site observations.
The map is centered on registry-derived city coordinates. Circle size reflects published trial activity.
Below are current trials with one or more ClinicalTrials.gov site observations in this city. Results are paginated 50 per page, with recruiting studies shown first.
Trials with sites in Johannesburg
384 linked trials · page 1 of 8Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With MelanomaNCT07476326 · 2026-09-09 · 2 site observations
RECRUITING
A Continued Access Study for Participants Transitioning From ViiV Healthcare-sponsored or ViiV Healthcare-collaborative Parent Studies for HIV TreatmentNCT07393659 · 2026-07-21 · 1 site observation
RECRUITING
A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan FastingNCT07613307 · 2026-07-15 · 1 site observation
RECRUITING
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes MellitusNCT07662044 · 2026-07-06 · 1 site observation
RECRUITING
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes MellitusNCT07662109 · 2026-07-06 · 1 site observation
RECRUITING
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DMNCT07667803 · 2026-06-29 · 2 site observations
RECRUITING
Testing the WeCare Intervention to Address Mental Health and Medication Adherence Challenges Among MSM in South AfricaNCT07226323 · 2025-12-01 · 1 site observation
RECRUITING
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular DiseaseNCT07181109 · 2025-09-22 · 4 site observations
RECRUITING
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic PhenotypeNCT07190222 · 2025-09-17 · 1 site observation
RECRUITING
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)NCT06926868 · 2025-09-11 · 1 site observation
RECRUITING
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular DiseaseNCT07064473 · 2025-07-22 · 5 site observations
RECRUITING
Project Vuselela FeasibilityNCT07117656 · 2025-07-13 · 1 site observation
RECRUITING
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast CancerNCT06790693 · 2025-04-09 · 1 site observation
RECRUITING
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With DapagliflozinNCT06677060 · 2025-03-14 · 1 site observation
RECRUITING
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood PressureNCT06742723 · 2025-03-03 · 1 site observation
RECRUITING
A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV TreatmentsNCT06337032 · 2024-08-27 · 2 site observations
RECRUITING
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart FailureNCT06424288 · 2024-06-17 · 1 site observation
RECRUITING
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney FunctionNCT06307652 · 2024-04-12 · 1 site observation
RECRUITING
Immunogenicity and Safety of Hecolin® in HIV Positive/Negative Adults and in ChildrenNCT06306196 · 2024-04-04 · 1 site observation
RECRUITING
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)NCT06103864 · 2023-11-23 · 3 site observations
RECRUITING
Rezafungin for Treatment of Pneumocystis Pneumonia in HIV AdultsNCT05835479 · 2023-11-14 · 2 site observations
RECRUITING
A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast CancerNCT05894239 · 2023-09-08 · 2 site observations
RECRUITING
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination TherapyNCT05646862 · 2023-06-07 · 1 site observation
RECRUITING
Reducing Mortality in Adults With Advanced HIV Disease (REVIVE)NCT05580666 · 2023-05-08 · 1 site observation
RECRUITING
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine TherapyNCT05774951 · 2023-03-31 · 2 site observations
RECRUITING
Gathering Records to Evaluate Antiretroviral Treatment-South AfricaNCT04149782 · 2019-12-01 · 1 site observation
RECRUITING
Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South AfricaNCT05539989 · 2026-12-31 · 1 site observation
WITHDRAWN
Safety and Efficacy of Ga68-IAC PET/CT for Diagnosis and Clinical Management in Metastatic Breast Cancer PatientsNCT04480619 · 2025-10-30 · 1 site observation
NOT_YET_RECRUITING
Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 YearsNCT06281119 · 2025-10-03 · 1 site observation
ACTIVE_NOT_RECRUITING
Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIVNCT07055451 · 2025-08-12 · 1 site observation
ACTIVE_NOT_RECRUITING
Protecting Against HIV Vaccine Misinformation With Adolescent Girls and Young Women in South AfricaNCT06700447 · 2025-07-24 · 1 site observation
ACTIVE_NOT_RECRUITING
Mental Health and Medication Adherence Among MSM in South AfricaNCT06880172 · 2025-05-26 · 1 site observation
COMPLETED
Cities for Better Health Childhood Obesity Prevention InitiativeNCT06855563 · 2025-04-30 · 1 site observation
ENROLLING_BY_INVITATION
Developing Interventions for Protecting HIV-Exposed Uninfected Infants Against Severe InfectionsNCT07052409 · 2025-04-10 · 1 site observation
ENROLLING_BY_INVITATION
A Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB12 (Proposed Pembrolizumab Biosimilar) to Keytruda® in Non-small Cell Lung Cancer (BENITO Study)NCT06687369 · 2024-12-30 · 2 site observations
ACTIVE_NOT_RECRUITING
Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk AsthmaNCT06676319 · 2024-11-07 · 1 site observation
ACTIVE_NOT_RECRUITING
A Phase I/II Multicenter, Open-Label Study of Lu-177-DOTAGA-IAC, for the Treatment of Angiogenic Breast Cancer Patients.NCT04469127 · 2024-09-30 · 1 site observation
UNKNOWN
Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)NCT06497504 · 2024-09-17 · 1 site observation
ACTIVE_NOT_RECRUITING
Evaluating the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibodies in Healthy ParticipantsNCT05959707 · 2024-08-14 · 2 site observations
SUSPENDED
Developing Screening Clinical Breast Examination Implementation Strategies in South AfricaNCT06233383 · 2024-06-01 · 1 site observation
COMPLETED
Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and AdultsNCT06062238 · 2024-03-05 · 5 site observations
ACTIVE_NOT_RECRUITING
Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance TherapyNCT06029595 · 2023-11-26 · 1 site observation
TERMINATED
MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural MesotheliomaNCT06097728 · 2023-11-09 · 2 site observations
ACTIVE_NOT_RECRUITING
A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor NaiveNCT05879822 · 2023-10-30 · 2 site observations
ACTIVE_NOT_RECRUITING
A Global Study of Volrustomig (MEDI5752) Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy for Participants With Metastatic Non-small Cell Lung Cancer.NCT05984277 · 2023-10-24 · 2 site observations
ACTIVE_NOT_RECRUITING
An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)NCT05952557 · 2023-10-05 · 2 site observations
ACTIVE_NOT_RECRUITING
A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic PainNCT05838755 · 2023-09-20 · 1 site observation
TERMINATED
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma ExacerbationsNCT06052267 · 2023-08-30 · 1 site observation
ACTIVE_NOT_RECRUITING
A Study of Tobemstomig + Nab-Paclitaxel Compared With Pembrolizumab + Nab-Paclitaxel in Participants With Previously Untreated, PD-L1-Positive, Locally-Advanced Unresectable or Metastatic Triple-Negative Breast CancerNCT05852691 · 2023-07-18 · 1 site observation
ACTIVE_NOT_RECRUITING
The CATALYST StudyNCT05937698 · 2023-05-30 · 2 site observations
TERMINATED
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