Sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Clinical research sponsor

Published trials1,564
Recruiting shown16
Roles2
SourceClinicalTrials.gov

Clinical trials

60 shown
Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATGNCT07216391 · lead sponsor · 2026-07-29
RECRUITING
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes MellitusNCT07142252 · lead sponsor · 2026-05-14
RECRUITING
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort StudyNCT06730113 · lead sponsor · 2025-03-12
RECRUITING
Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat ChangeNCT06325722 · lead sponsor · 2024-08-28
RECRUITING
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric DoseNCT06223555 · lead sponsor · 2024-08-23
RECRUITING
Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic RateNCT06044935 · lead sponsor · 2024-01-08
RECRUITING
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy ExpenditureNCT05545306 · lead sponsor · 2023-06-06
RECRUITING
A Natural History Study of Metabolic Sizing in Health and DiseaseNCT05398783 · lead sponsor · 2022-10-25
RECRUITING
Early Tracking of Childhood Health Determinants (ETCHED) StudyNCT03481829 · lead sponsor · 2022-04-14
RECRUITING
Clinical and Molecular Characteristics of Primary Aldosteronism in BlacksNCT03374215 · lead sponsor · 2017-12-14
RECRUITING
Natural History of Noncirrhotic Portal HypertensionNCT02417740 · lead sponsor · 2015-07-27
RECRUITING
New Heart Imaging Techniques to Evaluate Possible Heart DiseaseNCT01399385 · lead sponsor · 2011-07-06
RECRUITING
Physical and Behavioral Traits of Overweight and Obese AdultsNCT00428987 · lead sponsor · 2007-03-08
RECRUITING
Urinary Vitamin C Loss in Diabetic SubjectsNCT00071526 · lead sponsor · 2006-04-11
RECRUITING
Diabetes and Heart Disease Risk in BlacksNCT00001853 · lead sponsor · 1998-10-21
RECRUITING
Genetic Studies of Insulin and DiabetesNCT00001987 · lead sponsor · 1976-02-01
RECRUITING
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With ObesityNCT05713799 · lead sponsor · 2026-10-12
NOT_YET_RECRUITING
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and MetabolismNCT06690294 · lead sponsor · 2026-10-12
NOT_YET_RECRUITING
Effects of Meal Macronutrients on Postprandial LipidsNCT07313787 · lead sponsor · 2026-10-12
NOT_YET_RECRUITING
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and AdultsNCT07388537 · lead sponsor · 2026-10-12
NOT_YET_RECRUITING
Platform Trial in Stage 1 Diabetes: Comparing Golimumab vs PlaceboNCT07683026 · lead sponsor · 2026-08-08
NOT_YET_RECRUITING
Pilot Study of Isocaloric Time Restricted Eating on Ketone Metabolism and ImmunoregulationNCT06169137 · lead sponsor · 2024-09-04
COMPLETED
STOP-T1D Low-Dose (ATG)NCT04291703 · lead sponsor · 2023-11-01
TERMINATED
Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 DiabetesNCT03929601 · lead sponsor · 2023-10-30
ACTIVE_NOT_RECRUITING
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)NCT05743244 · lead sponsor · 2023-10-19
ACTIVE_NOT_RECRUITING
The Impact of the COVID-19 Pandemic on Eating Behavior and Weight ChangeNCT04896060 · lead sponsor · 2022-09-01
COMPLETED
Anti-TNFα to Delay or Prevent Progression to Stage 3 T1DNCT04729296 · lead sponsor · 2021-07-01
WITHDRAWN
A Multiple Ascending Dose Trial Investigating Safety, Tolerability and Pharmacokinetics of NNC0361-0041NCT04279613 · lead sponsor · 2020-11-23
COMPLETED
Methyldopa for Reduction of DQ8 Antigen Presentation in At-Risk Subjects for Type 1 DiabetesNCT03396484 · lead sponsor · 2020-09-01
WITHDRAWN
Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)NCT04209075 · lead sponsor · 2020-03-10
COMPLETED
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsNCT03520660 · lead sponsor · 2018-10-19
ACTIVE_NOT_RECRUITING
Brain Dopamine Function in Human ObesityNCT03648892 · lead sponsor · 2018-09-21
COMPLETED
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes MellitusNCT03428945 · lead sponsor · 2018-08-15
TERMINATED
Effect of Isocaloric Ultra Processed Versus Unprocessed Diets on Insulin SensitivityNCT03189121 · lead sponsor · 2017-11-20
COMPLETED
Empaglifozin in Early Diabetic Kidney DiseaseNCT03173963 · lead sponsor · 2017-05-27
WITHDRAWN
Title: Therapeutic Targets in African-American Youth With Type 2 DiabetesNCT02960659 · lead sponsor · 2017-05-09
COMPLETED
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor AgonistsNCT03049462 · lead sponsor · 2017-03-13
COMPLETED
Immune Effects of Oral Insulin in Relatives at Risk for Type 1 Diabetes Mellitus (TN20)NCT02580877 · lead sponsor · 2016-01-01
COMPLETED
Quantifying the Persistence of Metabolic Adaptation and Weight Regain Following Extreme Weight LossNCT02544009 · lead sponsor · 2015-09-05
COMPLETED
Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in People With Insulin Receptor MutationsNCT02457897 · lead sponsor · 2015-04-17
COMPLETED
Cross Calibration of Two Dual Energy Densitometers and Comparison of Regional Adipose Tissue Measurements by iDXA and MRINCT02346474 · lead sponsor · 2015-01-24
COMPLETED
ATG-GCSF in New Onset Type 1 DiabetesNCT02215200 · lead sponsor · 2014-12-01
COMPLETED
Compassionate Use of Metreleptin in Previously Treated People With Partial LipodystrophyNCT02262806 · lead sponsor · 2014-10-14
ACTIVE_NOT_RECRUITING
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenNCT00862433 · lead sponsor · 2014-10-10
COMPLETED
Compassionate Use of Metreleptin in Previously Treated People With Generalized LipodystrophyNCT02262832 · lead sponsor · 2014-10-09
ACTIVE_NOT_RECRUITING
Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy VolunteersNCT02404870 · lead sponsor · 2014-09-16
COMPLETED
TODAY2 Phase 2 Follow-upNCT02310724 · lead sponsor · 2014-03-01
COMPLETED
Investigation of the Gut Microbiota in Regulating Nutrient Absorption in HumansNCT02037295 · lead sponsor · 2014-01-14
COMPLETED
Study of the Effect of a Very-Low-Carbohydrate Diet on Energy ExpenditureNCT01967563 · lead sponsor · 2013-12-03
TERMINATED
Mechanisms of Diabetic Kidney Disease in American IndiansNCT01878045 · lead sponsor · 2013-11-07
COMPLETED
Identifying Risk for Diabetes and Heart Disease in WomenNCT01809288 · lead sponsor · 2013-09-26
COMPLETED
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese IndividualsNCT01862796 · lead sponsor · 2013-05-31
COMPLETED
Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - PhoenixNCT01812694 · lead sponsor · 2013-03-28
COMPLETED
CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1NCT01773707 · lead sponsor · 2013-03-01
COMPLETED
Short-term Effects of Leptin in People With LipodystrophyNCT01778556 · lead sponsor · 2013-01-26
COMPLETED
Energy Expenditure Responses to Different TemperaturesNCT01568671 · lead sponsor · 2012-04-24
COMPLETED
Healthy Lifestyle in PregnancyNCT01585454 · lead sponsor · 2012-03-27
WITHDRAWN
Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes MellitusNCT01083108 · lead sponsor · 2011-03-31
TERMINATED
TODAY2 Phase 1 Immediate Post-Intervention Observational Follow-up StudyNCT01364350 · lead sponsor · 2011-03-01
COMPLETED
Molecular and Clinical Profile of Diabetes Mellitus and Its ComplicationsNCT01105858 · lead sponsor · 2010-11-16
SUSPENDED

Sponsor roles

collaborator1,308
lead sponsor256

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.