Sponsor

GlaxoSmithKline

Clinical research sponsor

Published trials1,579
Recruiting shown24
Roles2
SourceClinicalTrials.gov

Clinical trials

60 shown
A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-2)NCT07780656 · lead sponsor · 2026-09-11
RECRUITING
A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)NCT07602855 · lead sponsor · 2026-09-09
RECRUITING
A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) [EMBOLD Prostate-302]NCT07802704 · lead sponsor · 2026-09-01
RECRUITING
A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)NCT07645248 · lead sponsor · 2026-09-01
RECRUITING
A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-1)NCT07780669 · lead sponsor · 2026-08-27
RECRUITING
A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-2)NCT07782996 · lead sponsor · 2026-08-27
RECRUITING
A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-1)NCT07780643 · lead sponsor · 2026-08-27
RECRUITING
A Comparative Study to Investigate the Difference in Blood Levels of Two Different Formulations of GSK5784283NCT07712393 · lead sponsor · 2026-07-17
RECRUITING
A Study of Depemokimab in Participants of 6 to 11 Years of AgeNCT07671001 · lead sponsor · 2026-06-25
RECRUITING
A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia in an Older Adult Population Aged 76 Years or Older in FinlandNCT07502560 · lead sponsor · 2026-03-31
RECRUITING
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 AsthmaNCT07456033 · lead sponsor · 2026-03-13
RECRUITING
First-Time-in-Human Study of GSK5471713 in Adults With mCRPCNCT07332455 · lead sponsor · 2026-02-10
RECRUITING
A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)NCT07371468 · lead sponsor · 2026-02-10
RECRUITING
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid TumorsNCT07277270 · lead sponsor · 2025-12-03
RECRUITING
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 InflammationNCT07177339 · lead sponsor · 2025-10-20
RECRUITING
Open-label Extension Study in Participants With Early Alzheimer's DiseaseNCT07105709 · lead sponsor · 2025-08-14
RECRUITING
A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]NCT07099898 · lead sponsor · 2025-08-11
RECRUITING
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)NCT06961214 · lead sponsor · 2025-06-23
RECRUITING
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 InflammationNCT06959095 · lead sponsor · 2025-06-20
RECRUITING
A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate CancerNCT06990880 · lead sponsor · 2025-06-12
RECRUITING
A Study to Compare the Relative Potency of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152a to HFA-134a in Mild Asthmatics Aged 18 to 65 InclusiveNCT06433921 · lead sponsor · 2024-08-14
RECRUITING
Depemokimab Asthma Imaging and Bronchoscopy Sub-StudyNCT06979323 · lead sponsor · 2024-07-19
RECRUITING
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With AsthmaNCT05757102 · lead sponsor · 2023-04-24
RECRUITING
A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib StudyNCT04641247 · lead sponsor · 2021-04-16
RECRUITING
A Study to Investigate the Effect of Omeprazole and Cyclosporine on Velzatinib in Healthy ParticipantsNCT07862114 · lead sponsor · 2026-10-16
NOT_YET_RECRUITING
Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Extracellular Vesicles (EVs), Patient-derived Organoid (PDOs)s and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)NCT06405230 · lead sponsor · 2025-10-10
TERMINATED
A Study to Assess the Potential for Airway Sensitivity Reactions With Propellants HFA-152a (Test) and HFA-134a (Reference) Administered Via Pressurized Inhalers in Adults With Mild AsthmaNCT06702462 · lead sponsor · 2025-03-11
COMPLETED
A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled AsthmaNCT06748053 · lead sponsor · 2025-02-10
ACTIVE_NOT_RECRUITING
Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)NCT06497504 · lead sponsor · 2024-09-17
ACTIVE_NOT_RECRUITING
Study of the Effect of HFA-152a and HFA-134a Propellants on Mucociliary Clearance in Healthy ParticipantsNCT06506266 · lead sponsor · 2024-07-29
COMPLETED
Retrospective Analysis of Systemic Glucocorticoid Mediated Long-term Effects, Patient Pathways and Economic Burden Across Multiple IndicationsNCT06488703 · lead sponsor · 2024-07-01
COMPLETED
A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)NCT06472076 · lead sponsor · 2024-06-10
ACTIVE_NOT_RECRUITING
A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 InclusiveNCT06433908 · lead sponsor · 2024-06-04
COMPLETED
A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With AsthmaNCT06261957 · lead sponsor · 2024-05-31
COMPLETED
Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled AsthmaNCT06372496 · lead sponsor · 2024-04-16
ACTIVE_NOT_RECRUITING
REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive StudyNCT06041386 · lead sponsor · 2024-03-20
ACTIVE_NOT_RECRUITING
A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary DiseaseNCT06154837 · lead sponsor · 2023-11-27
ACTIVE_NOT_RECRUITING
Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's DiseaseNCT06079190 · lead sponsor · 2023-10-20
TERMINATED
A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic PainNCT05838755 · lead sponsor · 2023-09-20
TERMINATED
A Study to Evaluate the Safety and Efficacy of Fluticasone Furoate (FF)/Umeclidinium(UMEC)/Vilanterol (VI) in Participants With Chronic Obstructive Pulmonary Disease (COPD)NCT04923347 · lead sponsor · 2023-06-06
COMPLETED
Green (Sustainable) VENTOLIN - Pharmacokinetics (PK) Study in Healthy ParticipantsNCT05791565 · lead sponsor · 2023-04-03
COMPLETED
A Study in Healthy Japanese Participants to Evaluate the Safety and Pharmacokinetics of OtilimabNCT05304130 · lead sponsor · 2023-02-08
WITHDRAWN
Phase 1, Single and Repeat Dose Study to Assess Safety, Tolerability, and Pharmacokinetics (PK) of GSK3923868 in Participants With Chronic Obstructive Pulmonary Disease (COPD)NCT05677347 · lead sponsor · 2023-01-23
COMPLETED
A Study to Compare the Pharmacokinetics (PK) of Depemokimab When Delivered With a Safety Syringe Device (SSD) or an Autoinjector in Healthy Adult ParticipantsNCT05602025 · lead sponsor · 2022-12-13
COMPLETED
To Evaluate Real-World Effectiveness of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol (FF/UMEC/VI) in a Single Inhaler (Trelegy Ellipta) in Participants With Symptomatic COPDNCT05535972 · lead sponsor · 2022-10-14
COMPLETED
A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung CancerNCT05565378 · lead sponsor · 2022-10-14
ACTIVE_NOT_RECRUITING
Efficacy and Safety of GSK3923868 Inhalation Powder, During Experimental Human Rhinovirus Infection in Participants With Mild AsthmaNCT05398198 · lead sponsor · 2022-06-09
COMPLETED
Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal PolypsNCT05274750 · lead sponsor · 2022-04-22
COMPLETED
Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2)NCT05281523 · lead sponsor · 2022-04-18
COMPLETED
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid TumorsNCT05277051 · lead sponsor · 2022-03-22
ACTIVE_NOT_RECRUITING
An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103)NCT05243680 · lead sponsor · 2022-03-01
COMPLETED
Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Participants With Non-small Cell Lung Cancer (NSCLC) - Sub-study 3NCT06926673 · lead sponsor · 2021-12-23
COMPLETED
Study of GSK3511294 in Healthy Chinese ParticipantsNCT05140200 · lead sponsor · 2021-12-10
COMPLETED
A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics (PD) of GSK3888130B in Healthy ParticipantsNCT05131971 · lead sponsor · 2021-11-01
COMPLETED
A Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With an ExtensionNCT04880031 · lead sponsor · 2021-09-30
COMPLETED
A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy ParticipantsNCT05044325 · lead sponsor · 2021-09-20
TERMINATED
Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled AsthmaNCT04937387 · lead sponsor · 2021-07-29
COMPLETED
Efficacy and Safety Study of Mepolizumab 100 Milligram (mg) Subcutaneous (SC) in Indian Participants Aged Greater Than or Equal to (>=) 18 Years With Severe Eosinophilic AsthmaNCT04276233 · lead sponsor · 2021-06-29
COMPLETED
Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular DiseaseNCT04915755 · lead sponsor · 2021-06-28
ACTIVE_NOT_RECRUITING
Molecular Disease Characterization Initiative (MDCI)NCT04772053 · lead sponsor · 2021-05-25
TERMINATED

Sponsor roles

lead sponsor1,082
collaborator497

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.