Clinical trial

A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014)

NCT00106145

Study summary

ClinicalTrials.gov

A Notch Signalling Pathway Inhibitor for Patients With Advanced Breast Cancer (0752-014)

Design: INTERVENTIONAL · Status: COMPLETED · Phase: PHASE1

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Drugs and interventions used in this trial

5 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

DRUG · Unmapped registry intervention Comparator: MK0752, Notch Inhibitor Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Comparator: MK0752, Notch Inhibitor - 450 mg Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Comparator: MK0752, Notch Inhibitor - 3 days on, 4 off Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Comparator: MK0752, Notch Inhibitor - 1 day on, 6 off Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Comparator: MK0752, Notch Inhibitor - 3 days on, 4 off 350 mg Find medicine records · Find other trials using this name

StatusCOMPLETED

Study typeINTERVENTIONAL

Start date2005-04-01

PhasePHASE1

Conditions

Advanced Breast Cancerunresolved

Other Solid Tumorsunresolved

Interventions

Comparator: MK0752, Notch InhibitorDRUG

Comparator: MK0752, Notch Inhibitor - 450 mgDRUG

Comparator: MK0752, Notch Inhibitor - 3 days on, 4 offDRUG

Comparator: MK0752, Notch Inhibitor - 1 day on, 6 offDRUG

Comparator: MK0752, Notch Inhibitor - 3 days on, 4 off 350 mgDRUG

Sponsors & collaborators

Merck Sharp & Dohme LLClead sponsor

Registry source

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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.