Clinical trial

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

NCT04556773

Drugs and interventions used in this trial

7 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

Search this trial's interventions

DRUG · Mapped RxNorm record Trastuzumab deruxtecan Normalized identity: trastuzumab deruxtecanView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Durvalumab Normalized identity: durvalumabView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Paclitaxel Normalized identity: paclitaxelView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Capivasertib Normalized identity: capivasertibView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Anastrozole Normalized identity: anastrozoleView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Fulvestrant Normalized identity: fulvestrantView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Capecitabine Normalized identity: capecitabineView linked drug · Find medicine records · Find other trials using this name

Study at a glance

Registry-backed

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

Design: INTERVENTIONAL · Status: ACTIVE NOT RECRUITING · Phase: PHASE1

Read study objectives, eligibility and outcome measures at ClinicalTrials.gov

StatusACTIVE_NOT_RECRUITING

Study typeINTERVENTIONAL

Start date2020-12-17

PhasePHASE1

Conditions

Metastatic Breast Cancerunresolved

Interventions

Trastuzumab deruxtecanDRUG · verified · RxNorm: trastuzumab deruxtecan

DurvalumabDRUG · verified · RxNorm: durvalumab

PaclitaxelDRUG · verified · RxNorm: paclitaxel

CapivasertibDRUG · verified · RxNorm: capivasertib

AnastrozoleDRUG · verified · RxNorm: anastrozole

FulvestrantDRUG · verified · RxNorm: fulvestrant

CapecitabineDRUG · verified · RxNorm: capecitabine

Sponsors & collaborators

AstraZenecalead sponsor

Daiichi Sankyo Co., Ltd.collaborator

Daiichi Sankyo Company, Limitedcollaborator

Mapped research locations

SeoulSouth Korea4 TaipeiTaiwan4 New YorkNew York, United States2 MoscowRussia2 São PauloBrazil2 Porto AlegreBrazil2 Chapel HillNorth Carolina, United States1 Saint PetersburgRussia1 LeuvenBelgium1 TaichungTaiwan1 QuébecQuebec, Canada1 Fort WorthTexas, United States1

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT04556773 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.