Clinical trial

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT01935947

Study summary

ClinicalTrials.gov

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Design: INTERVENTIONAL · Status: TERMINATED · Phase: PHASE2

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Drugs and interventions used in this trial

8 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

DRUG · Mapped RxNorm record Azacitidine Normalized identity: azacitidine View linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Docetaxel Normalized identity: docetaxel View linked drug · Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Entinostat Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Gemcitabine Hydrochloride Normalized identity: gemcitabine hydrochloride View linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Irinotecan Hydrochloride Normalized identity: irinotecan hydrochloride View linked drug · Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Laboratory Biomarker Analysis Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Pemetrexed Disodium Normalized identity: pemetrexed disodium View linked drug · Find medicine records · Find other trials using this name

StatusTERMINATED

Study typeINTERVENTIONAL

Start date2013-05-01

PhasePHASE2

Conditions

Recurrent Non-Small Cell Lung Carcinomaunresolved

Stage IIIA Non-Small Cell Lung Cancerunresolved

Stage IIIB Non-Small Cell Lung Cancerunresolved

Stage IV Non-Small Cell Lung Cancerunresolved

Interventions

AzacitidineDRUG · verified · RxNorm: azacitidine

DocetaxelDRUG · verified · RxNorm: docetaxel

EntinostatDRUG

Gemcitabine HydrochlorideDRUG · verified · RxNorm: gemcitabine hydrochloride

Irinotecan HydrochlorideDRUG · verified · RxNorm: irinotecan hydrochloride

Laboratory Biomarker AnalysisOTHER

Pemetrexed DisodiumDRUG · verified · RxNorm: pemetrexed disodium

Sponsors & collaborators

National Cancer Institute (NCI)lead sponsor

Mapped research locations

BaltimoreMaryland, United States2 Los AngelesCalifornia, United States1 CharlestonSouth Carolina, United States1 Newport BeachCalifornia, United States1

Registry source

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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.