Clinical trial

COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure

NCT01786512

Drugs and interventions used in this trial

4 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

Search this trial's interventions

DRUG · Unmapped registry intervention Omecamtiv Mecarbil Matrix F1 Formulation Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Omecamtiv Mecarbil Matrix F2 Formulation Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Placebo Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention Omecamtiv Mecarbil Swellable Core Technology F2 Find medicine records · Find other trials using this name

Study at a glance

Registry-backed

COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure

Design: INTERVENTIONAL · Status: COMPLETED · Phase: PHASE2

Read study objectives, eligibility and outcome measures at ClinicalTrials.gov

StatusCOMPLETED

Study typeINTERVENTIONAL

Start date2013-02-26

PhasePHASE2

Conditions

Modified Release Oral Formulationunresolved

Left Ventricular Systolic Dysfunctionunresolved

Chronic Heart Failureunresolved

History of Chronic Heart Failureunresolved

Left Ventricular Ejection Fractionunresolved

Pharmacokineticsunresolved

Echocardiogramunresolved

Interventions

Omecamtiv Mecarbil Matrix F1 FormulationDRUG

Omecamtiv Mecarbil Matrix F2 FormulationDRUG

PlaceboDRUG

Omecamtiv Mecarbil Swellable Core Technology F2DRUG

Sponsors & collaborators

Cytokineticslead sponsor

Mapped research locations

BudapestHungary3 MinneapolisMinnesota, United States2 PragueCzechia2 KrakowPoland2 BrnoCzechia2 HoustonTexas, United States1 ChicagoIllinois, United States1 Los AngelesCalifornia, United States1 BaltimoreMaryland, United States1 St LouisMissouri, United States1 AtlantaGeorgia, United States1 MiamiFlorida, United States1

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT01786512 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.