Clinical trial

Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension

NCT00353652

StatusCOMPLETED

Study typeINTERVENTIONAL

Start date2005-01-01

PhasePHASE4

Study timeline

Study start (unknown)2005-01-01Date precision: month

Registry last updated2019-02-06

Observed by CureCurrent2026-10-07

Recorded dates are source observations, not predictions. Missing milestones are not estimated.

Conditions

Hypertensionunresolved

Interventions

Study#1: chlorthalidone (CTD), titrated doseDRUG

Study #1: spironolactone (SP), titrated doseDRUG

Study# 2 chlorthalidone (CTD), fixed doseDRUG

Study# 2 spironolactone (SP), fixed doseDRUG

Study# 2 irbsesartan (IR), fixed doseDRUG

Sponsors & collaborators

University of Texas Southwestern Medical Centerlead sponsor

National Heart, Lung, and Blood Institute (NHLBI)collaborator

Mapped research locations

DallasTexas, United States2

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT00353652 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.