Clinical trial

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

NCT07202000

StatusRECRUITING

Study typeINTERVENTIONAL

Start date2026-06-03

PhasePHASE2

Study timeline

Study start (actual)2026-06-03Date precision: day

Registry last updated2026-07-09

Observed by CureCurrent2026-10-07

Recorded dates are source observations, not predictions. Missing milestones are not estimated.

Conditions

Heart Failure With Preserved Ejection Fractionunresolved

Interventions

Activin ligand-trap biological therapyDRUG

Placebo, Normal SalineDRUG

Sponsors & collaborators

Massachusetts General Hospitallead sponsor

American Heart Associationcollaborator

University of Michigancollaborator

Oakland Universitycollaborator

Mapped research locations

BostonMassachusetts, United States1

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT07202000 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.