Clinical trial

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

NCT02194738

Drugs and interventions used in this trial

17 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

Search this trial's interventions

PROCEDURE · Unmapped registry intervention Biospecimen Collection Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Carboplatin Normalized identity: carboplatinView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Cisplatin Normalized identity: cisplatinView linked drug · Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Clinical Observation Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Computed Tomography Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Crizotinib Normalized identity: crizotinibView linked drug · Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Cytology Specimen Collection Procedure Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Echocardiography Test Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Erlotinib Normalized identity: erlotinibView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Gemcitabine Hydrochloride Normalized identity: gemcitabine hydrochlorideView linked drug · Find medicine records · Find other trials using this name

BIOLOGICAL · Unmapped registry intervention Nivolumab Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Paclitaxel Normalized identity: paclitaxelView linked drug · Find medicine records · Find other trials using this name

BIOLOGICAL · Unmapped registry intervention Pembrolizumab Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Pemetrexed Normalized identity: pemetrexedView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Pemetrexed Disodium Normalized identity: pemetrexed disodiumView linked drug · Find medicine records · Find other trials using this name

OTHER · Unmapped registry intervention Placebo Administration Find medicine records · Find other trials using this name

PROCEDURE · Unmapped registry intervention Positron Emission Tomography Find medicine records · Find other trials using this name

Study at a glance

Registry-backed

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Design: INTERVENTIONAL · Status: ACTIVE NOT RECRUITING · Phase: NA

Read study objectives, eligibility and outcome measures at ClinicalTrials.gov

StatusACTIVE_NOT_RECRUITING

Study typeINTERVENTIONAL

Start date2014-09-26

PhaseNA

Conditions

Stage IB Lung Non-Small Cell Carcinoma AJCC v7unresolved

Stage II Lung Non-Small Cell Cancer AJCC v7unresolved

Stage IIA Lung Cancer AJCC v8unresolved

Stage IIB Lung Cancer AJCC v8unresolved

Stage IIIA Lung Cancer AJCC v8unresolved

Stage IIIA Lung Non-Small Cell Cancer AJCC v7unresolved

Stage IIIB Lung Cancer AJCC v8unresolved

Interventions

Biospecimen CollectionPROCEDURE

CarboplatinDRUG · verified · RxNorm: carboplatin

CisplatinDRUG · verified · RxNorm: cisplatin

Clinical ObservationOTHER

Computed TomographyPROCEDURE

CrizotinibDRUG · verified · RxNorm: crizotinib

Cytology Specimen Collection ProcedureOTHER

Echocardiography TestPROCEDURE

ErlotinibDRUG · verified · RxNorm: erlotinib

Gemcitabine HydrochlorideDRUG · verified · RxNorm: gemcitabine hydrochloride

NivolumabBIOLOGICAL

PaclitaxelDRUG · verified · RxNorm: paclitaxel

PembrolizumabBIOLOGICAL

PemetrexedDRUG · verified · RxNorm: pemetrexed

Pemetrexed DisodiumDRUG · verified · RxNorm: pemetrexed disodium

Placebo AdministrationOTHER

Positron Emission TomographyPROCEDURE

Sponsors & collaborators

National Cancer Institute (NCI)lead sponsor

Mapped research locations

Las VegasNevada, United States35 HonoluluHawaii, United States13 DenverColorado, United States12 PittsburghPennsylvania, United States11 OmahaNebraska, United States11 CincinnatiOhio, United States10 ChicagoIllinois, United States9 SeattleWashington, United States9 IndianapolisIndiana, United States9 HoustonTexas, United States8 BaltimoreMaryland, United States8 St LouisMissouri, United States8

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT02194738 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.