Clinical trial

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

NCT05007106

Drugs and interventions used in this trial

12 registered

These interventions are listed by ClinicalTrials.gov. An RxNorm link indicates a mapped medicine record; the registry name alone is not proof of a specific branded formulation.

Search this trial's interventions

BIOLOGICAL · Unmapped registry intervention Pembrolizumab/Vibostolimab Co-Formulation Find medicine records · Find other trials using this name

BIOLOGICAL · Unmapped registry intervention Pembrolizumab Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Lenvatinib Normalized identity: lenvatinibView linked drug · Find medicine records · Find other trials using this name

DRUG · Unmapped registry intervention 5-Fluorouracil Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Cisplatin Normalized identity: cisplatinView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Paclitaxel Normalized identity: paclitaxelView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Gemcitabine Normalized identity: gemcitabineView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Carboplatin Normalized identity: carboplatinView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Docetaxel Normalized identity: docetaxelView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Bevacizumab Normalized identity: bevacizumabView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Capecitabine Normalized identity: capecitabineView linked drug · Find medicine records · Find other trials using this name

DRUG · Mapped RxNorm record Oxaliplatin Normalized identity: oxaliplatinView linked drug · Find medicine records · Find other trials using this name

Study at a glance

Registry-backed

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

Design: INTERVENTIONAL · Status: COMPLETED · Phase: PHASE2

Read study objectives, eligibility and outcome measures at ClinicalTrials.gov

StatusCOMPLETED

Study typeINTERVENTIONAL

Start date2021-09-16

PhasePHASE2

Conditions

Uterine Cervical Neoplasmsunresolved

Endometrial Neoplasmsunresolved

Squamous Cell Carcinoma of Head and Neckverified · MONDO: head and neck squamous cell carcinoma

Gallbladder Neoplasmsunresolved

Cholangiocarcinomaverified · MONDO: cholangiocarcinoma

Esophageal Neoplasmsunresolved

Triple Negative Breast Neoplasmsunresolved

Hepatocellular Carcinomaverified · MONDO: hepatocellular carcinoma

Urinary Bladder Neoplasmsverified · MONDO: urinary bladder neoplasm

Ovarian Neoplasmsunresolved

Stomach Neoplasmsunresolved

Interventions

Pembrolizumab/Vibostolimab Co-FormulationBIOLOGICAL

PembrolizumabBIOLOGICAL

LenvatinibDRUG · verified · RxNorm: lenvatinib

5-FluorouracilDRUG

CisplatinDRUG · verified · RxNorm: cisplatin

PaclitaxelDRUG · verified · RxNorm: paclitaxel

GemcitabineDRUG · verified · RxNorm: gemcitabine

CarboplatinDRUG · verified · RxNorm: carboplatin

DocetaxelDRUG · verified · RxNorm: docetaxel

BevacizumabDRUG · verified · RxNorm: bevacizumab

CapecitabineDRUG · verified · RxNorm: capecitabine

OxaliplatinDRUG · verified · RxNorm: oxaliplatin

Sponsors & collaborators

Merck Sharp & Dohme LLClead sponsor

Mapped research locations

SeoulSouth Korea3 TaipeiTaiwan2 IstanbulTurkey (Türkiye)2 AnkaraTurkey (Türkiye)2 New YorkNew York, United States1 HoustonTexas, United States1 TorontoOntario, Canada1 MadridSpain1 ParisFrance1 BerlinGermany1 DetroitMichigan, United States1 MilanItaly1

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT05007106 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.