Clinical trial

PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer

NCT07426094

StatusRECRUITING

Study typeINTERVENTIONAL

Start date2026-03-19

PhasePHASE2 / PHASE3

Study timeline

Study start (actual)2026-03-19Date precision: day

Registry last updated2026-07-21

Observed by CureCurrent2026-10-07

Recorded dates are source observations, not predictions. Missing milestones are not estimated.

Conditions

Prostate Cancerunresolved

Brachytherapyunresolved

Stereotactic Body Radiation Therapy (SBRT)unresolved

Dose Escalation: Solid Tumorsunresolved

Regionally Advanced Prostate Cancerunresolved

Interventions

Ultrahypofractionated Whole-Pelvis RadiotherapyRADIATION

SBRT-Based Prostate Radiotherapy (No Boost)RADIATION

Ablative Prostate BoostRADIATION

Intermediate Nodal Dose EscalationRADIATION

Higher Nodal Dose EscalationRADIATION

Androgen Deprivation Therapy (ADT)DRUG

Androgen Receptor Pathway Inhibitors (ARPIs)DRUG

Sponsors & collaborators

Affidea Nu-med Center of Oncological DIagnostics and Therapylead sponsor

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT07426094 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.