Clinical trial

Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)

NCT06854614

StatusACTIVE_NOT_RECRUITING

Study typeINTERVENTIONAL

Start date2025-03-01

PhasePHASE4

Study timeline

Study start (actual)2025-03-01Date precision: day

Registry last updated2026-09-30

Observed by CureCurrent2026-10-07

Recorded dates are source observations, not predictions. Missing milestones are not estimated.

Conditions

Obesityunresolved

Interventions

Comprehensive weight lossOTHER

Enhanced lifestyle changesOTHER

TirzepatideDRUG · verified · RxNorm: tirzepatide

Naltrexone-BupropionDRUG

Phentermine-TopiramateDRUG

Semaglutide (Wegovy®)DRUG

Sponsors & collaborators

The Cleveland Cliniclead sponsor

Mapped research locations

ClevelandOhio, United States1

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT06854614 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.