Clinical trial

The COSMYC Trial (COmbined Suppression of MYC)

NCT06922318

StatusRECRUITING

Study typeINTERVENTIONAL

Start date2025-08-19

PhasePHASE2

Study timeline

Study start (actual)2025-08-19Date precision: day

Registry last updated2026-06-18

Observed by CureCurrent2026-10-07

Recorded dates are source observations, not predictions. Missing milestones are not estimated.

Conditions

Metastatic Castration-resistant Prostate Cancerunresolved

Interventions

Testosterone cypionateDRUG · verified · RxNorm: testosterone cypionate

EnzalutamideDRUG · verified · RxNorm: enzalutamide

Luteinizing hormone-releasing hormone (LHRH) analogueDRUG

Sponsors & collaborators

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkinslead sponsor

Zenith Epigeneticscollaborator

National Cancer Institute (NCI)collaborator

Mapped research locations

BaltimoreMaryland, United States1

Registry source

Open the source record to verify current eligibility, contacts, locations and registry updates.

Open NCT06922318 on ClinicalTrials.gov ↗

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.