Condition
Diabetes Mellitus Type 1
ClinicalTrials.gov condition label
Clinical trials
54 shownHOME-AHCL: Home-Based Implementation of an Advanced Hybrid Closed-Loop System With Telemonitoring in Type 1 DiabetesNCT07492992 · 2026-04-22
RECRUITINGChanges in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict AppNCT07814508 · 2026-02-01
RECRUITINGCBTi for the Treatment of Insomnia in Type 1 DiabetesNCT07091318 · 2025-12-01
RECRUITINGEfficacy and Safety of the APGO Algorithm for Automated Insulin DeliveryNCT07320495 · 2025-06-19
RECRUITINGType 1 Diabetes and Diabetes DistressNCT06936280 · 2025-04-01
RECRUITINGSotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney DiseaseNCT06217302 · 2024-10-31
RECRUITINGThe Effect of Light Therapy on Cellular Energy and Oxidative Stress in Healthy Adults and Type 1 Diabetic PatientsNCT07833865 · 2026-10-01
NOT_YET_RECRUITINGA Study of the Safety and Efficacy of Pancreatic Endocrine Cell Clusters Implanted Into the Omentum of Type 1 Diabetes Patients With Severe HypoglycemiaNCT06651515 · 2025-04-01
WITHDRAWNSMARTCLOTH. Design, Implementation and Study of the Effectiveness and Usability of a Digital Tablecloth for Self-management of Diet in Diabetic Patients.NCT06623708 · 2024-10-01
UNKNOWNReal-life Follow-up of the Physical Activity in Type 1 Diabetes Participants Equipped With an Insulin Pump With Hybrid Closed LoopNCT07015970 · 2024-03-05
COMPLETEDFinnDiane LifeOne Study - Impact of Ageing on People With Type 1 DiabetesNCT07289204 · 2024-01-29
ENROLLING_BY_INVITATIONFeasibility of Non-invasive Glucose Monitoring by Using Photothermal DeflectometryNCT06088615 · 2023-11-08
COMPLETEDPsychiatric Disorders Related to Diabetes Mellitus Type 1NCT05477433 · 2022-08-01
UNKNOWNPsychiatric Disorders Related to Diabetes Mellitus Type 1 Among Children in EgyptNCT05477173 · 2022-08-01
UNKNOWNA Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 DiabetesNCT02624804 · 2017-06-27
COMPLETEDClinical Trial Assessing the GNbAC1 in Patients With Onset of Type 1 Diabetes Within 4 YearsNCT03179423 · 2017-06-14
COMPLETEDUse of Stem Cells in Diabetes Mellitus Type 1NCT02940418 · 2017-02-19
UNKNOWNZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed GlucagonNCT02916251 · 2016-12-01
COMPLETEDGastric Ultrasound of Diabetic and Non-Diabetic Patients Following Preoperative Fasting InstructionsNCT02888951 · 2016-08-01
UNKNOWNContinuous Glucose Monitoring During Intecorse in Young Adults With Type 1 DiabetesNCT02750111 · 2016-05-01
UNKNOWNThe iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic PancreasNCT02701257 · 2016-03-01
TERMINATEDLong Term CGM Treatment in Patients With Type 1 Diabetes Treated With Insulin InjectionsNCT02465411 · 2015-06-01
COMPLETEDComparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections to Reach HbA1c Targets in Children and Adolescents With Type 1 DiabetesNCT02403375 · 2015-05-17
COMPLETEDBlood Glucose Control With BioChaperone Insulin Lispro Compared to Insulin Lispro (Humalog®) After Ingestion of a Standardized MealNCT02344992 · 2015-01-01
COMPLETEDA Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 DiabetesNCT02213146 · 2014-08-01
COMPLETEDA Study of Intracellular Signaling in Muscle and Fat Cells During KetosisNCT02157155 · 2014-06-01
COMPLETEDA Double-blinded, Randomised, Four-period Crossover Euglycemic Clamp Trial Investigating the Dose-response and Dose-exposure Relationship of BioChaperone Insulin Lispro in Three Different Doses in Subjects With Type 1 DiabetesNCT02146651 · 2014-05-01
COMPLETEDMoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without DiabetesNCT02545062 · 2014-05-01
UNKNOWNA Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic PancreasNCT02092220 · 2014-04-01
COMPLETEDEffect of Microvesicles and Exosomes Therapy on β-cell Mass in Type I Diabetes Mellitus (T1DM)NCT02138331 · 2014-04-01
UNKNOWNA Prospective, Randomized, Double-blind, Placebo Controlled Study to Assess the Impact of ORMD-0801 (Insulin Capsules) on the Exogenous Insulin Requirements of Type 1 DiabeticsNCT02094534 · 2014-03-01
COMPLETEDTransplantation of Autologous Stem Cells for the Treatment of Type 1 Diabetes MellitusNCT02644759 · 2014-02-01
COMPLETEDA Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 DiabetesNCT02029924 · 2013-12-01
COMPLETEDEffects of Exercise and Inhibition of Dipeptidyl Peptidase-4 on Insulin Secretion in Subjects With Type 1 DiabetesNCT02127047 · 2013-11-01
COMPLETEDTrial to Compare the Relative Pharmacodynamic Properties of Different Glucagon DosagesNCT01916265 · 2013-08-01
COMPLETEDDiameter Changes of Retinal Vessels During HypoxiaNCT01689090 · 2012-11-01
COMPLETEDMixed Meal Test in Type 1 Diabetes: Optimization of Artificial Pancreas-Pilot StudyNCT01800734 · 2012-10-01
UNKNOWNMeasuring and Monitoring Blood Glucose Levels Utilizing Non-invasive Blood Glucose Monitoring DeviceNCT01508065 · 2012-09-01
UNKNOWNAssessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 PatientsNCT02538120 · 2012-05-01
COMPLETEDThe Influence of Partial Remission Phase of Type 1 Diabetes on Patient OutcomeNCT02220257 · 2012-01-01
UNKNOWNPharmacokinetic and Pharmacodynamic Properties of BIOD-105 and BIOD-107 Compared to Humalog® in Subjects With Type 1 DiabetesNCT01334151 · 2011-03-01
COMPLETEDThe Effect of Supplementation With Two Different Doses of Vitamin D on Bone Mineral Density, Vitamin D Levels and Hand Grip Strength in Children With Diabetes Mellitus Type 1NCT01277913 · 2011-01-01
COMPLETEDA Study of the Rules for Insulin Dosing in Patients Using Multiple Daily InjectionsNCT01045954 · 2010-01-01
UNKNOWNEffects of XOMA 052 on Insulin Production in Type 1 DiabetesNCT01788033 · 2009-09-01
COMPLETEDComparison of the Management of Post-prandial Hyperglycemia by Multiple Bolus CalculatorsNCT01050868 · 2009-06-01
COMPLETEDNatural History of Autoimmune Diabetes and Its ComplicationsNCT00896610 · 2009-05-13
TERMINATEDNovel Therapy to Preserve Beta Cell Function in New Onset Type 1 DiabetesNCT00837759 · 2009-02-01
TERMINATEDAssessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy IndividualsNCT00813228 · 2009-01-06
COMPLETEDA Monocenter, Open-Label Glucose Clamp Study Examining the Metabolic Effect of Insulin Infusion Intervals for Basal Insulin Infusion in Patients With Type I DiabetesNCT00772356 · 2008-01-01
COMPLETEDComparison of Basal (Fasting) Glycemic Control in Type 1 Diabetic Patients With CSII Achieved by the Circadian Slide Ruler Scale or Flat Basal RateNCT00569452 · 2006-01-01
COMPLETEDBasal Analog Study - Comparison of Lantus or Levemir With NPH Insulin From T1DM DiagnosisNCT01271517 · 2005-09-01
UNKNOWNA Study Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections With Insulin Lispro and GlargineNCT00468754 · 2003-07-01
COMPLETEDGlulisine Pre- and PostmealNCT00290043 · 2001-12-01
COMPLETEDSolitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing ImmunosuppressionNCT00006505 · 2000-11-16
COMPLETEDCommon interventions
Humalog®DRUG4PlaceboDRUG3Accu-Chek Spirit Insulin PumpDEVICE2BioChaperone insulin lisproDRUG2SitagliptinDRUG2Accu-Chek Combo Kit mg DE/deDEVICE1Accu-Chek Insight Pump SystemDEVICE1ACTnowBEHAVIORAL1Adipose mesenchymal cells with bone marrow mononuclear cellsBIOLOGICAL1Allogeneic Pancreatic Endocrine Cell ClustersBIOLOGICAL1BioChaperone human insulinDRUG1BioChaperone insulin lispro 0.1U/KgDRUG1BioChaperone insulin lispro 0.2U/KgDRUG1BioChaperone insulin lispro 0.4U/KgDRUG1Bionic PancreasDEVICE1Clamp-Mixed Meal ArmOTHER1Comparator insulin pumpDEVICE1Contact Detach infusion setDEVICE1COX inhibitorOTHER1COX inhibitor + L-NG-monomethyl arginine citrateOTHER1DetemirDRUG1Device: Insulin pump TouchCare Nano A8 with the APGO systemDEVICE1Dexcom G4 or later generationDEVICE1diabetes mellitus type 1BEHAVIORAL1DiamydBIOLOGICAL1
Leading sponsors
Hoffmann-La Roche5Adocia4National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)4Assiut University2Massachusetts General Hospital2University of Aarhus2Air Liquide Healthcare Spain1Alessandro Doria1Azienda Ospedaliera Universitaria Integrata Verona1Biodel1Charles University, Czech Republic1Clalit Health Services1Diabetes Care Center1Diamontech AG1Dr. Orit Hamiel1
Trial status mix
COMPLETED29
UNKNOWN13
RECRUITING6
TERMINATED3
ENROLLING_BY_INVITATION1
NOT_YET_RECRUITING1
WITHDRAWN1
Phase mix
NA18
PHASE212
PHASE111
PHASE43
PHASE32
EARLY_PHASE11
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.