Condition

Osteoarthritis (OA) of the Knee

ClinicalTrials.gov condition label

Clinical trials3

Recruiting1

Common interventions5

Lead sponsors shown2

Clinical trials

3 shown

Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/ObesityNCT07065591 · 2026-08-30

RECRUITING

Optimization of Obesity for Total Knee Replacement With Glucagon-like Peptide-1 Receptor AgonistNCT06807970 · 2025-09-01

ACTIVE_NOT_RECRUITING

LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)NCT06670651 · 2025-03-21

ENROLLING_BY_INVITATION

Common interventions

Control (Standard treatment)OTHER1Glucagon-like peptide-1 receptor agonists (GLP 1 RA)DRUG1MetforminDRUG1PlaceboOTHER1total knee arthroplasty deviceDEVICE1

Leading sponsors

The University of Hong Kong2LinkBio Corp.1

Trial status mix

ACTIVE_NOT_RECRUITING1

ENROLLING_BY_INVITATION1

RECRUITING1

Phase mix

EARLY_PHASE12

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.