Condition
Lymphangioleiomyomatosis
ClinicalTrials.gov condition label
Clinical trials
21 shownTuberous Sclerosis Complex and Lymphangioleiomyomatosis Pregnancy Registry (TSC-LAM Registry)NCT06160310 · 2023-07-01
RECRUITINGTSC Biosample Repository and Natural History DatabaseNCT05676099 · 2016-01-01
RECRUITINGSafety and Durability of Sirolimus for Treatment of LAMNCT02432560 · 2015-03-01
RECRUITINGStudy of the Disease Process of LymphangioleiomyomatosisNCT00001465 · 1995-12-18
RECRUITINGBreath Analysis and Arterial Stiffness in Patients With Respiratory DiseasesNCT05727852 · 2023-01-30
ENROLLING_BY_INVITATIONLymphangioleiomyomatosis, a Study on Cathepsin KNCT05323370 · 2022-05-31
COMPLETEDFeasibility of [11C]Acetate-PET in LAM and TSCNCT05467397 · 2021-08-30
ACTIVE_NOT_RECRUITINGBenefits of Pulmonary Rehabilitation in Patients With Severe Lymphangioleiomyomatosis (LAM)NCT04184193 · 2019-12-03
COMPLETEDBiomarkers for Tuberous Sclerosis Complex (BioTuScCom)NCT02654340 · 2018-08-01
TERMINATEDThe Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation PatientsNCT02859194 · 2016-05-31
COMPLETEDCharacterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and AngiomyolipomaNCT02325505 · 2016-04-01
COMPLETEDSafety of Simvastatin in LAM and TSCNCT02061397 · 2014-03-01
COMPLETEDPulmonary Rehabilitation in LymphangioleiomyomatosisNCT02009241 · 2013-11-01
COMPLETEDBevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign DiseaseNCT01552434 · 2012-10-16
TERMINATEDPulmonary Hypertension in LymphangioleiomyomatosisNCT00960895 · 2009-08-01
COMPLETEDDoxycycline In Lymphangioleiomyomatosis (LAM)NCT00989742 · 2009-07-01
COMPLETEDEffect of Fasting on the Size of Abdominal Lymphatic Tumors in WomenNCT00552955 · 2007-10-26
COMPLETEDRole of Helicobacter Pylori and Its Toxins in Lung and Digestive System DiseasesNCT00366509 · 2006-09-18
COMPLETEDTrial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAMNCT00490789 · 2005-10-01
UNKNOWNRAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAMNCT00457964 · 2005-08-01
COMPLETEDRapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAMNCT00457808 · 2002-12-01
COMPLETEDCommon interventions
Pulmonary RehabilitationOTHER2sirolimusDRUG2[11C]acetateDRUG124h urineOTHER1Assessment of arterial stiffness using the VaSera VS-1500NDIAGNOSTIC_TEST1BevacizumabBIOLOGICAL1Breath test using the Compact PTR-TOF-MSDIAGNOSTIC_TEST1Buccal (cheek) swabPROCEDURE1CetuximabBIOLOGICAL1DoxycyclineDRUG1EverolimusDRUG1Everolimus Oral ProductDRUG1Genetic TestingGENETIC1Laboratory Biomarker AnalysisOTHER1Pharmacological StudyOTHER1PhlebotomyPROCEDURE1PlaceboDRUG1Portable cardiac monitor "CardioQvark"DIAGNOSTIC_TEST1RAD001DRUG1Rapamycin, sirolimusDRUG1SimvastatinDRUG1Sirolimus Oral ProductDRUG1TemsirolimusDRUG1Tissue donation after routine clinical procedureOTHER1Toshibia Aquilion One CTDEVICE1
Leading sponsors
National Heart, Lung, and Blood Institute (NHLBI)3Children's Hospital Medical Center, Cincinnati2Brigham and Women's Hospital1Cardiff University1CENTOGENE GmbH Rostock1David M. Ritter1Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires1I.M. Sechenov First Moscow State Medical University1InCor Heart Institute1M.D. Anderson Cancer Center1National Tuberous Sclerosis Association1Schön Klinik Berchtesgadener Land1University Hospital, Tours1University of Cincinnati1University of Nottingham1
Trial status mix
COMPLETED12
RECRUITING4
TERMINATED2
ACTIVE_NOT_RECRUITING1
ENROLLING_BY_INVITATION1
UNKNOWN1
Phase mix
PHASE25
PHASE14
NA2
PHASE41
Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.