Condition

Optic Neuritis

ClinicalTrials.gov condition label

Clinical trials36

Recruiting6

Common interventions25

Lead sponsors shown15

Clinical trials

36 shown

Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation ResearchNCT07623668 · 2026-05-28

Efgartigimod for the Treatment of Acute Optic NeuritisNCT06453694 · 2025-08-12

Light Stimulation to Improve Visual Function After Optic Neuritis in Persons with Multiple SclerosisNCT06389968 · 2024-08-01

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)NCT05017142 · 2020-04-14

Retinal Neuro-vascular Coupling in Patients With Multiple SclerosisNCT03401879 · 2018-02-01

Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)NCT02521311 · 2017-02-28

Early Prediction of Outcomes Following Optic Neuritis: Development and Acceptability of a Prognostic ToolNCT07704294 · 2026-09-01

NOT_YET_RECRUITING

Fampridine-SR and Optic Neuritis RecoveryNCT04148781 · 2022-03-22

Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)NCT04289909 · 2020-12-01

Optical Coherence Tomography and Optic Neuritis Not Related to Multiple SclerosisNCT03963310 · 2020-09-14

Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic NerveNCT05605951 · 2020-08-15

Diagnosis of ON With or Without MS or NMOSDNCT04131764 · 2019-10-04

Effect of Transorbital Electrical STIMulation of Optic Nerve on Remyelination After an Acute Optic NeuritisNCT04042363 · 2019-07-10

Optic Neuritis Differential Diagnosis StudyNCT03370965 · 2019-06-07

The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CISNCT03451955 · 2018-01-19

3D FLAIR Versus Coronal T2-WI MRI in Detecting Optic Neuritis (FLACON)NCT04792866 · 2018-01-01

Post-COntrast 3D SE T1 Versus Coronal SE T1-WI MRI in Detecting Optic Neuritis (COCON)NCT04793087 · 2018-01-01

Pupillometry Dynamic Measures in Patients Without Ocular or Neurological DiseaseNCT02894281 · 2016-06-01

Linking Optic Nerve MRI and the Retinal Axonal Loss After Optic NeuritisNCT03651362 · 2016-02-01

Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled TrialNCT01962571 · 2014-11-25

Amiloride Clinical Trial In Optic NeuritisNCT01802489 · 2013-02-01

Interest of Dynamic Measures of the Pupil in Optic NeuritisNCT02004054 · 2012-12-01

Optical Coherence Tomography in Multiple Sclerosis PatientsNCT01774123 · 2012-08-01

Optic Neuritis Recovery After Oral or IV CorticosteroidsNCT01524250 · 2012-03-01

Neuroprotection With Phenytoin in Optic NeuritisNCT01451593 · 2011-11-01

Ampyra for Optic Neuritis in Multiple SclerosisNCT01337986 · 2011-05-01

Lipoic Acid as a Treatment for Acute Optic NeuritisNCT01294176 · 2011-01-01

Visual Reconstitution Therapy After Optic NeuritisNCT01274702 · 2010-05-01

Neuroprotection and Repair in Optic NeuritisNCT01073813 · 2010-02-01

Simvastatin Treatment of Patients With Acute Optic NeuritisNCT00261326 · 2006-09-01

Safety and Efficacy Study of Erythropoietin as add-on Therapy of Methylprednisolone to Treat Acute Optic NeuritisNCT00355095 · 2006-08-01

Biobank For MS And Other Demyelinating DiseasesNCT00445367 · 2006-05-01

ACTIVE_NOT_RECRUITING

Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.NCT00037115 · 2002-05-01

Long Term Study of Avonex Therapy Following a First Attack of Multiple SclerosisNCT00179478 · 2001-02-01

Optic Neuritis Treatment Trial (ONTT)NCT00000146 · 1988-07-01

Longitudinal Optic Neuritis Study (LONS)NCT00000147 · 1988-07-01

Common interventions

Leading sponsors

Fondation Ophtalmologique Adolphe de Rothschild5 National Eye Institute (NEI)2 Accelerated Cure Project for Multiple Sclerosis1 Anastasia Vishnevetsky, MD, MPH1 Beth Israel Deaconess Medical Center1 Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts1 Courtney Casserly1 Experimental and Clinical Research Center, a cooperation between the Max Delbrück Center for Molecul1 Friedemann Paul1 Glostrup University Hospital, Copenhagen1 Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH1 Institut National de la Santé Et de la Recherche Médicale, France1 Jagannadha R Avasarala1 King's College London1 London Health Sciences Centre1

Trial status mix

COMPLETED18

UNKNOWN7

RECRUITING6

TERMINATED2

ACTIVE_NOT_RECRUITING1

NOT_YET_RECRUITING1

WITHDRAWN1

Phase mix

PHASE29

NA7

PHASE36

PHASE42

EARLY_PHASE11

PHASE11

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.