Condition

Left Ventricular Dysfunction

ClinicalTrials.gov condition label

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Search results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.

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Connected source records

This is the original ClinicalTrials.gov condition label, found in 47 distinct published trials. It is kept separate from a MONDO disease identifier until a specific normalization is supported. Related interventions are co-recorded in studies; they are not medical recommendations.

Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.

Clinical trials47

Recruiting5

Common interventions25

Lead sponsors shown15

Clinical trials

47 shown

Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT NonrespondersNCT05760924 · 2024-11-01

Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse RemodelingNCT06356727 · 2024-01-03

Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure PatientsNCT05769036 · 2023-10-01

Prevalence and Risk Factors asSOciated With CArdiac comorbiDIty in psoriAsisNCT04950218 · 2021-09-01

Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)NCT04752293 · 2021-05-19

Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE)NCT07776964 · 2026-10-29

NOT_YET_RECRUITING

Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk FactorNCT06088212 · 2024-07-01

HIDRAdenitis Suppurativa and HEART DiseaseNCT05989945 · 2023-08-01

ACTIVE_NOT_RECRUITING

Acute Cardiac Dysfunction in Critical IllnesNCT05860504 · 2023-05-29

Cardiac Structure and Function in Patients with Cystic FibrosisNCT06084468 · 2023-01-01

ACTIVE_NOT_RECRUITING

Cardiovascular Assessment of Pediatric Cancer SurvivorsNCT05939089 · 2023-01-01

Early Assessment of Impaired Cardiac Function in Patients With Diabetes MellitusNCT05484817 · 2022-06-01

Evaluation of the BIOTRONIK AutoAdapt Algorithm for Continuous Automatic Adaptive Cardiac ResynchronizationNCT04774523 · 2021-08-31

Detection of Heart Conditions Using Artificial IntelligenceNCT04933890 · 2021-06-01

HIS-Purkinje Conduction System Pacing Optimized Trial of Cardiac Resynchronization TherapyNCT04561778 · 2021-04-15

Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial FibrillationNCT04694092 · 2020-11-05

Effects of Home-based Exercise Rehabilitation on Healthcare Utilization in HeartMate 3 PatientsNCT04942353 · 2020-10-19

Cardiac Dysfunction in Critically Ill Covid-19 PatientsNCT06197256 · 2020-05-07

Cardiac Dysfunction in Critically Ill Patients With COVID-19NCT04524234 · 2020-04-20

Hemodynamic Characteristics of Patients With SARS-CoV-2NCT04337983 · 2020-03-13

Ivabradine in Cirrhotic CardiomyopathyNCT04111133 · 2020-01-01

How is COGNItive Function Affected by Cardiac Resynchronisation Therapy?NCT03755570 · 2019-06-21

Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection FractionNCT04397302 · 2019-01-13

Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With AnthracyclinesNCT05728632 · 2019-01-01

Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related CardiotoxicityNCT03089502 · 2018-04-01

Reprogramming to Prevent Progressive Pacemaker-induced RemodellingNCT03627585 · 2017-08-01

LV Endocardial CRT for Patients With Intermediate QRS WidthNCT03573427 · 2016-04-28

Cardiac Function and Microcirculation: Type 2 DIABetes and ECHOcardiographic Changes Over TimeNCT02956577 · 2016-03-16

PARACHUTE V PercutAneous Ventricular RestorAtion in Chronic Heart FailUre Due to Ischemic HearT DiseasE.NCT02543632 · 2015-08-01

AI-ECG for Time-Resolved Prediction of HFrEFNCT07519434 · 2014-02-01

Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart FailureNCT01822808 · 2013-01-01

Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular SeptumNCT01609738 · 2012-11-01

Outcome of Patients Treated With IABPNCT04405856 · 2012-02-01

INcrease Of VAgal TonE in CHFNCT01303718 · 2011-02-01

A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging SystemNCT01076296 · 2010-02-01

Pilot Study of Remote Ischemic Preconditioning in Heart FailureNCT01128790 · 2009-10-01

Levosimendan In Patients Undergoing LVAD ImplantationNCT03659851 · 2009-06-01

Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study)NCT00824005 · 2009-03-01

VIVID - Valvular and Ventricular Improvement Via iCoapsys Delivery - Feasibility StudyNCT00512005 · 2008-01-01

Effects of Left Ventricular Pacing Optimilization on Cardiac Perfusion, Contractile Force, and Clinical Performance in Patients With Ventricular Dysfunction and Heart FailureNCT00551681 · 2007-11-01

Use of 3-D Blood Pool Scintigraphy to Guide Left Ventricular Pacing Lead Placement in Patients Requiring Cardiac Resynchronization TherapyNCT02669290 · 2007-01-01

Effects of Viagra on Heart Function in Patients With Heart FailureNCT00781508 · 2006-12-01

Predicting Response to Cardiac Resynchronization Therapy in Heart FailureNCT00359372 · 2006-07-28

Left Ventricular DYsfunction in DiAbetesNCT01971125 · 2006-07-01

Risk Stratification of Cancer Therapy-Related Cardiac Dysfunction Using AI-Enhanced ElectrocardiographyNCT07515859 · 2006-05-01

St. Vincent's Screening To Prevent Heart Failure StudyNCT00921960 · 2005-01-01

RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral ValveNCT00120276 · 2004-06-01

Common interventions

EchocardiographyDIAGNOSTIC_TEST2 Adult stem cellsBIOLOGICAL1 Assessment of cardiovascular risk factor, endocrine hormones and related biomarkerDIAGNOSTIC_TEST1 BetablockerDRUG1 Betablocker + ivabradineDRUG1 biventricular pacemaker with epicardial left ventricular leadDEVICE1 Biventricular PacingDEVICE1 Cardiac magnetic resonance imagingDIAGNOSTIC_TEST1 Cardiac Resynchronization Therapy Devices with Defibrillator Function (CRT-D) or CRT-D Leads ReplacementDEVICE1 CardioFit® SystemDEVICE1 Coronary CTDIAGNOSTIC_TEST1 CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right and Left Ventricular PacingDEVICE1 CRT-D or CRT-D Leads Replacement with New Lead Implantation to Left Bundle Branch and Inactivation of Conventional Right Ventricular PacingDEVICE1 Disease management programOTHER1 ECG, Echocardiography, cTnI, NT-ProBNPDIAGNOSTIC_TEST1 Echo-based assessment of the acute hemodynamic effect of the CRT AutoAdapt feature.PROCEDURE1 EchocardiographyDEVICE1 EchocardiographyPROCEDURE1 Echocardiography AV optimizationPROCEDURE1 Exercise RehabilitationOTHER1 Frontal Assessment BatteryDIAGNOSTIC_TEST1 GuidedOTHER1 Home-based Exercise Rehabilitation.BEHAVIORAL1 Hospital Anxiety and Depression ScaleDIAGNOSTIC_TEST1 HOT-CRTDEVICE1

Mapped drugs appearing in these trials

Shared trial participation only; not evidence of efficacy or approval.

hydralazine1 isosorbide dinitrate1 levosimendan 2.5 MG/ML Injectable Solution1 nebivolol1 placebo1 sildenafil1

Leading sponsors

Herlev and Gentofte Hospital 3 Myocor 2 Sahlgrenska University Hospital 2 Tomsk National Research Medical Center of the Russian Academy of Sciences 2 University Health Network, Toronto 2 Azienda Ospedaliera Universitaria Integrata Verona 1 Baker Heart and Diabetes Institute 1 Bicetre Hospital 1 BioControl Medical 1 Biotronik SE & Co. KG 1 CardioKinetix, Inc 1 Eko Devices, Inc. 1 GE Healthcare 1 Giulio Stefanini 1 Heart Care Foundation 1

Trial status mix

COMPLETED23

UNKNOWN10

RECRUITING5

TERMINATED4

ACTIVE_NOT_RECRUITING2

NOT_YET_RECRUITING1

SUSPENDED1

WITHDRAWN1

Phase mix

NA16

PHASE33

PHASE22

PHASE11

PHASE41

Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.