Drug & intervention

isosorbide dinitrate

RxCUI 6058

Clinical trials1
Recruiting0
Related conditions1
Synonyms1

RxNorm ingredient and formulation relationships

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Background context

Isosorbide dinitrate

Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent angina pectoris. It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine. It is taken by mouth or under the tongue. Common side effects include headache, lightheadedness with standing, and blurred vision. Severe side effects include low blood pressure. It is unclear if use in pregnancy is safe for the baby. It should not be used together with PDE5 Inhibitors. Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. Isosorbide dinitrate was first written about in 1939. It is on the World Health Organization's List of Essential Medicines. Isosorbide dinitrate is available as a generic medication. A long-acting form exists. In 2023, isosorbide was the 125th most commonly prescribed medication in the United States, with more than 5 million prescriptions.

Background only. Canonical identity remains RxNorm; clinical-trial relationships come from ClinicalTrials.gov.

Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.