autism
MONDO:0005260
Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior.
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Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
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Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
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Autism
Autism, also known as autism spectrum disorder (ASD), is a condition characterized by impairment in social communication and interaction, as well as a need or strong preference for predictability and routine, sensory processing differences, focused interests, or repetitive behaviors. Features of autism are present from early childhood and the condition typically persists throughout life. Autism is classified as a neurodevelopmental disorder, and a diagnosis requires professional assessment that these characteristics cause significant challenges in daily life beyond what is expected given a person's age and social environment. Because autism is a spectrum disorder, presentations vary and support needs range from minimal assistance to full-time, 24-hour care. Autism diagnoses have risen since the 1990s, largely because of broader diagnostic criteria, greater awareness, and wider access to assessment. Changing social demands may also play a role. The World Health Organization estimates that about 1 in 100 children were diagnosed between 2012 and 2021, noting an increasing trend. Surveillance studies suggest a similar share of the adult population would meet diagnostic criteria if formally assessed. Autism is highly heritable and involves many genes, while environmental factors appear to play a smaller, mainly prenatal role. Boys are diagnosed several times more often than girls, with girls being better at hiding autistic traits. Conditions such as anxiety, depression, attention deficit hyperactivity disorder (ADHD), epilepsy, as well as intellectual disability, are more com...
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.