Disease & disorder
brain neoplasm
MONDO:0021211
A neoplasm (disease) that involves the brain.
Research intelligence
Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
Medications under investigation
Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.
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MONDO disease family
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Recruiting studies by city
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Trial status
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Trial phase
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Study start year
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Investigated drug interventions
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Background context
brain neoplasm
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Clinical trials
40 shownSafety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP LossNCT06810544 · 2025-03-24
RECRUITINGBrodalumab in the Treatment of Immune-Related Adverse EventsNCT06673329 · 2025-03-11
RECRUITINGDetermining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal AssessmentNCT06352710 · 2023-06-12
RECRUITINGRemote Neuropsychological Assessment of Patients With Neurological Disorders and InjuriesNCT05819008 · 2023-03-10
RECRUITINGPrognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omicsNCT06001073 · 2022-12-05
RECRUITINGStudy of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast CancerNCT05386108 · 2022-08-31
RECRUITING68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor PatientsNCT05549024 · 2022-08-16
RECRUITINGBlood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain MetsNCT05317858 · 2022-08-12
RECRUITINGPhase I Study of JYP0322 in ROS1 Fusion-Positive Solid TumorsNCT06128148 · 2022-05-04
RECRUITINGStereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain MetastasesNCT04899908 · 2021-09-15
RECRUITING18F-DOPA II - PET Imaging OptimizationNCT04706910 · 2021-01-20
RECRUITINGEngineered TILs/CAR-TILs to Treat Advanced Solid TumorsNCT04842812 · 2021-01-01
RECRUITINGThe MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac StudyNCT04075305 · 2019-02-01
RECRUITINGAPL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsNCT03175224 · 2017-09-27
RECRUITINGNon-invasive Intracranial Pressure Monitoring in Brain Tumor PatientsNCT07286396 · 2026-01-01
NOT_YET_RECRUITINGPhase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast AgentNCT06322342 · 2024-08-15
COMPLETEDCALM: Managing Distress in Malignant Brain CancerNCT06180460 · 2023-11-10
COMPLETEDThe Effect of 360° Virtual Reality Movies on Fear and AnxietyNCT06199050 · 2023-06-16
COMPLETEDThe Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of ActionNCT05926336 · 2023-05-23
UNKNOWNPost Market Clinical Follow-up of CODMAN CERTAS Programmable ValveNCT05397106 · 2023-01-24
ACTIVE_NOT_RECRUITINGA Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid TumorsNCT05538130 · 2022-11-30
ACTIVE_NOT_RECRUITINGDynamic Decompressive CraniotomyNCT05051488 · 2022-04-30
UNKNOWNStudy of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.NCT04712721 · 2021-10-14
TERMINATEDNeuropsychology of Financial CapacityNCT05791006 · 2021-08-04
UNKNOWNImproving Social Cognition and Social Behaviour in Various Brain DisordersNCT06330298 · 2021-05-31
UNKNOWNA Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsNCT04644315 · 2021-05-24
TERMINATEDThe Registry of Oncology Outcomes Associated With Testing and TreatmentNCT04028479 · 2021-05-05
COMPLETEDA FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain InvolvementNCT04543188 · 2021-01-08
TERMINATEDRandomised Trial Evaluating the Benefit of a Fitness Tracker Based Workout During RadiotherapyNCT04517019 · 2020-08-01
UNKNOWNClosed vs. Open Face Masks for Cranial RadiotherapyNCT04079595 · 2019-12-09
COMPLETEDIncreasing Diagnosis Rates While Reducing Examination Time: Can MR Fingerprinting Deliver on Its Promise?NCT06251830 · 2018-09-01
COMPLETEDUse of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy SurgeryNCT04344626 · 2018-07-16
WITHDRAWNCureOne Registry: Advanced Malignancy or Myelodysplasia, Tested by Standard Sequencing and Treated by Physician ChoiceNCT02900248 · 2017-10-02
TERMINATEDBevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II TrialNCT02655536 · 2017-08-01
UNKNOWNAn Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring DeviceNCT02773888 · 2015-12-01
SUSPENDEDTreatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART133NCT02541370 · 2015-06-01
COMPLETEDPatientSpot Formerly Known as ArthritisPowerNCT03840928 · 2015-04-01
UNKNOWNAssessing the Patient Experience in Cancer CareNCT01621295 · 2012-05-01
COMPLETEDUltrasound Guided Central Vein Catheterization and ComplicationsNCT01510743 · 2012-01-30
COMPLETEDSocial Cognition in Children Treated for a Brain TumourNCT01599052 · 2011-03-01
COMPLETEDDrugs being studied
Research locations
BostonMassachusetts, United States8HoustonTexas, United States8Los AngelesCalifornia, United States8New YorkNew York, United States7TampaFlorida, United States6TorontoOntario, Canada5EdmontonAlberta, Canada4LyonFrance4MadisonWisconsin, United States4MontrealQuebec, Canada4NashvilleTennessee, United States4San FranciscoCalifornia, United States4
Leading sponsors
Merck Sharp & Dohme LLC3Pfizer2Pharmacyclics LLC.2University Medical Center Groningen2AHS Cancer Control Alberta1Apollomics Inc.1AstraZeneca1AVM Biotechnology Inc1Brian Henick, MD1Brigham and Women's Hospital1British Columbia Cancer Agency1Cantonal Hospital of St. Gallen1Chinese PLA General Hospital1Copharos1CureOne1
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.