candidiasis
MONDO:0002026
Infection with the organism Candida.
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Directly mapped studies only · unique clinical trialsCurrent registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.
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Candidiasis
Candidiasis is a fungal infection due to any species of yeasts in the genus Candida or those that were formerly classified in genus Candida but are now classified in the genus Candidozyma. When it affects the mouth (oral candidiasis) it is commonly known as thrush. Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. Other symptoms may include soreness and problems swallowing. When it affects the vagina, it may be referred to as a yeast infection or thrush. Signs and symptoms include genital itching, burning, and sometimes a white "cottage cheese-like" discharge from the vagina. Yeast infections of the penis are less common and typically present with an itchy rash. Very rarely, yeast infections may become invasive, spreading to other parts of the body. This may result in fevers, among other symptoms. Finally, candidiasis of the esophagus is an important risk factor for contracting esophageal cancer in individuals with achalasia. More than 20 types of Candida may cause infection with Candida albicans being the most common. Infections of the mouth are most common among children less than one month old, the elderly, and those with weak immune systems. Conditions that result in a weak immune system include HIV/AIDS, the medications used after organ transplantation, diabetes, and the use of corticosteroids. Other risk factors include during breastfeeding, following antibiotic therapy, and the wearing of dentures. Vaginal infections occur more commonly during pregnancy, in those with weak immune systems, and following antibiotic therap...
Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.Drugs being studied
Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.