Disease & disorder

malaria

MONDO:0005136

Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly.Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.

Clinical trials40
Recruiting1
Drug concepts studied8
Synonyms0

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Clinical trials

40 shown
OPTImizing Malaria And HIV Treatment in a Shifting Landscape in AfricaNCT06967519 · 2025-12-18
RECRUITING
Diabetes, Metabolic Syndrome and Risk of Malaria in CameroonNCT06278181 · 2023-09-21
COMPLETED
Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIVNCT05385510 · 2023-01-10
COMPLETED
Baromètre Santé Adulte 2021-2022NCT05218304 · 2021-07-26
SUSPENDED
Optimizing Malaria Treatment for HIV-Malaria Co-infected IndividualsNCT04708496 · 2021-01-18
UNKNOWN
Improving Maternal heAlth by Reducing Malaria in African HIV WomenNCT03671109 · 2019-09-18
COMPLETED
Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian AdultsNCT03420053 · 2018-02-07
COMPLETED
Prevention of Malaria in HIV-uninfected Pregnant Women and InfantsNCT02793622 · 2016-09-01
COMPLETED
Leiden University Medical Center Mini Donor BankNCT02810613 · 2016-05-31
WITHDRAWN
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ PatientsNCT02527005 · 2015-09-01
COMPLETED
Dolutegravir Interactions With Artemisinin-based Combination TherapiesNCT02242799 · 2015-06-01
COMPLETED
Reducing the Burden of Malaria in HIV-Infected Pregnant Women and Their HIV-Exposed Children (PROMOTE-BC2)NCT02282293 · 2014-12-09
COMPLETED
Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and InfantsNCT02163447 · 2014-06-23
COMPLETED
Safety and Immunogenicity Study of Influenza Vaccines in HIV-infected and HIV-uninfected Pregnant Women in Western KenyaNCT01810731 · 2014-04-01
WITHDRAWN
Impact of TMP-SMX Prophylaxis on Malaria Infection and Immunity in Children in UgandaNCT02094508 · 2014-03-07
COMPLETED
Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT)NCT01921413 · 2013-07-01
COMPLETED
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)NCT01766830 · 2013-01-01
COMPLETED
Antimalarial Pharmacology in Children and Pregnant Women in UgandaNCT01717885 · 2012-08-01
COMPLETED
Pharmacology of Antimalarial Therapy With or Without Antiretroviral TherapyNCT01728961 · 2012-02-01
TERMINATED
Discontinuation of Trimethoprim-sulfamethoxazole Prophylaxis in Adults on Antiretroviral Therapy in KenyaNCT01425073 · 2012-02-01
COMPLETED
Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen RepertoiresNCT01214876 · 2010-08-01
COMPLETED
Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and ChildrenNCT01148459 · 2010-07-30
COMPLETED
Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant WomenNCT00993031 · 2009-12-15
COMPLETED
Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in KenyaNCT00914225 · 2009-09-01
COMPLETED
HIV Protease Inhibitors for the Prevention of Malaria in Ugandan ChildrenNCT00978068 · 2009-09-01
COMPLETED
Evaluation of Alternative Antimalarial Drugs for Malaria in PregnancyNCT00811421 · 2009-09-01
COMPLETED
Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAARTNCT00719602 · 2009-08-01
COMPLETED
Study of DDT and Loss of Clinically-Recognized Pregnancies in South AfricaNCT00878098 · 2009-06-01
COMPLETED
Pharmacokinetic Interaction Between the Antimalarial Combination Artemether/Lumefantrine and Combination Antiretroviral Therapy Including Lopinavir/Ritonavir in HIV-infected AdultsNCT00869700 · 2009-06-01
COMPLETED
The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon IslandsNCT01080989 · 2009-03-01
COMPLETED
Artemether/Lumefantrine and Nevirapine Interaction Study in HIV-infected AdultsNCT00790881 · 2008-10-01
COMPLETED
The Effect of Malaria on Disease Progression of HIV/AIDSNCT00499876 · 2007-10-01
COMPLETED
Role of Nitric Oxide in MalariaNCT00527163 · 2007-09-04
COMPLETED
Interactions Between HIV and Malaria in African ChildrenNCT00527800 · 2007-08-01
COMPLETED
Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected PatientsNCT00421473 · 2007-03-01
COMPLETED
Drug Interaction Study Between Antimalarial and Anti-HIV MedicationsNCT00266058 · 2005-12-01
COMPLETED
Relationship Between HIV and Malaria in Ugandan ChildrenNCT00356824 · 2005-11-01
COMPLETED
Pharmacokinetic Interactions Between Antiretroviral Agents and Antimalarial Drug CombinationsNCT00697892 · 2005-07-01
COMPLETED
In-Vivo Response of P. Falciparum to Antimalarial Treatment in HIV-Infected and HIV-Uninfected AdultsNCT00144352 · 2002-09-01
COMPLETED
Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate ResistanceNCT00137657 · 2002-02-01
COMPLETED

Leading sponsors

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.