Drug & intervention

nevirapine

RxCUI 53654

Clinical trials107
Recruiting0
Related conditions20
Synonyms9

Understanding this RxNorm record

RxNorm identifiers distinguish ingredients, specific strengths, dose forms, and branded products. They help connect equivalent terminology across data sources; an RxNorm entry does not by itself establish that a product is currently marketed, approved for a particular use, or appropriate for an individual.

Clinical-trial associations reflect registry-reported intervention names and verified mappings where available. A medication listed in a trial may be investigational for that condition. Consult the original study record and official prescribing information for indications and safety details.

Terminology source: National Library of Medicine RxNorm. Trial source: ClinicalTrials.gov.

RxNorm ingredient and formulation relationships

Source-verified product relationships. Every strength, delivery form and RxCUI remains a separate clinical concept.

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Background context

Nevirapine

Nevirapine (NVP), sold under the brand name Viramune among others, is a medication used to treat and prevent HIV/AIDS, specifically HIV-1. It is generally recommended for use with other antiretroviral medications. It may be used to prevent mother to child spread during birth but is not recommended following other exposures. It is taken by mouth. Common side effects include rash, headache, nausea, feeling tired, and liver problems. The liver problems and skin rash may be severe and should be checked for during the first few months of treatment. It appears to be safe for use during pregnancy. It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and works by blocking the function of reverse transcriptase. Nevirapine was approved for medical use in the United States in 1996. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.

Read on Wikipedia ↗ Wikidata Q263713 ↗
Background only. Canonical identity remains RxNorm; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

40 shown
Neuropsychiatric Side Effects of Efavirenz in Children Living With HIVNCT03227653 · 2017-06-19
COMPLETED
Efficacy of Rilpivirine-based Regimens as Switch Therapy From Nevirapine-based Regimens in HIV-infected PatientsNCT03664440 · 2016-12-01
COMPLETED
Study of HIV-Infected and Uninfected Pregnant Woman/Child Dyads in Gaborone, BotswanaNCT03088410 · 2016-08-22
COMPLETED
Antiretroviral Regime for Viral Eradication in NewbornsNCT02712801 · 2016-04-01
COMPLETED
Latency and Early Neonatal Provision of Antiretroviral Drugs Clinical TrialNCT02431975 · 2015-08-01
COMPLETED
Early Infant HIV Treatment in BotswanaNCT02369406 · 2015-05-04
ACTIVE_NOT_RECRUITING
Evaluation of Renal Function, Efficacy, and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir, to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremia and Impaired Renal Function (MK-0518-284)NCT02116660 · 2014-09-03
TERMINATED
A Pharmacokinetic Evaluation of Levonorgestrel Implant and Antiretroviral TherapyNCT01789879 · 2014-03-04
COMPLETED
Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-InfectedNCT01632891 · 2014-01-10
COMPLETED
A Study to Evaluate the Effects of Genetic Factors on the Pharmacokinetics of Antiretroviral Drugs During Pregnancy and LactationNCT02269462 · 2012-12-01
COMPLETED
Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study)NCT01637558 · 2012-11-01
COMPLETED
Influence of Nevirapine on HCV Viral LoadNCT01277627 · 2011-01-01
UNKNOWN
Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAARTNCT00719602 · 2009-08-01
COMPLETED
Nevirapine vs Ritonavir-boosted Lopinavir in ART Naive HIV-infected Adults in a Resource Limited SettingNCT01772940 · 2008-12-01
COMPLETED
Safety and Pharmacokinetic Study of Fixed Dose Combination of Zidovudine, Lamivudine, and Nevirapine in HIV-Infected Children in ThailandNCT00672412 · 2008-10-01
COMPLETED
Trial About Hepatic Security of Antiretroviral Treatment Based on Kaletra Versus Nevirapine in Co-infected HIV/HCV PatientsNCT00661349 · 2008-02-01
TERMINATED
The CogNaive Study: Assessing Changes in Neurocognitive Function in Treatment Naïve HIV-1 Positive SubjectsNCT00540137 · 2007-07-01
COMPLETED
Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TBNCT01805258 · 2007-06-01
COMPLETED
Using Nevirapine to Prevent Mother-to-Child HIV Transmission During BreastfeedingNCT00074412 · 2007-01-01
COMPLETED
Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving RifampinNCT00483054 · 2007-01-01
COMPLETED
Drug Levels of Tablet and Liquid Forms of Lamivudine, Nevirapine, and Stavudine in HIV Infected Thai ChildrenNCT00312091 · 2006-12-01
COMPLETED
NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV TransmissionNCT00089505 · 2006-11-01
COMPLETED
VENICE Study Nevirapine Full Dose/Dose EscalationNCT00704249 · 2006-07-01
COMPLETED
Evaluation of Two Anti-HIV Treatment Strategies in Resource-Limited South African CommunitiesNCT00255840 · 2006-07-01
COMPLETED
Trizivir Vs. Kaletra and Combivir for the Prevention of Mother-to-Child Transmission of HIVNCT00270296 · 2006-06-01
COMPLETED
Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving BirthNCT00109590 · 2006-06-01
COMPLETED
When to Start Anti-HIV Drugs in Children Infected With HIV (The PREDICT Study)NCT00234091 · 2006-04-01
COMPLETED
Pharmacokinetics Study on Nevirapine Resistance in TanzaniaNCT00294892 · 2006-02-01
COMPLETED
Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected ChildrenNCT00260078 · 2006-02-01
COMPLETED
Case-Control Viramune (Nevirapine) Toxicogenomics StudyNCT00310843 · 2006-02-01
COMPLETED
Antiviral Responses to NNRTI-Based vs. PI-Based ARV Therapy in HIV Infected Infants Who Have or Have Not Received Single Dose NVP for Prevention of Mother-to-Child Transmission of HIVNCT00307151 · 2005-12-01
COMPLETED
ATV/Ritonavir Nevirapine Interaction (USPAC)NCT00162149 · 2005-10-01
COMPLETED
Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at BirthNCT00102960 · 2005-07-01
COMPLETED
Pediatric Nevirapine Resistance StudyNCT00117728 · 2005-04-01
UNKNOWN
Zidovudine / Lamivudine + Nevirapine Twice Daily, Versus Tenofovir + Lamivudine + Nevirapine Once Daily in ARV-Naive PatientsNCT00199979 · 2005-04-01
UNKNOWN
Preventing Sexual Transmission of HIV With Anti-HIV DrugsNCT00074581 · 2005-02-01
COMPLETED
Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIVNCT00307502 · 2005-01-01
COMPLETED
Durability of Nevirapine-Based Antiretroviral RegimenNCT00703898 · 2004-11-01
COMPLETED
Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple Treatment With Analogues OnlyNCT00415090 · 2004-08-01
COMPLETED
Nevirapine Study for the Prevention of Maternal-Infant HIV Transmission in UgandaNCT00639938 · 2004-07-01
COMPLETED

Leading sponsors

National Institute of Allergy and Infectious Diseases (NIAID)45Boehringer Ingelheim21Abbott2Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections2Bamrasnaradura Infectious Diseases Institute2Bristol-Myers Squibb2Germans Trias i Pujol Hospital2Harvard School of Public Health (HSPH)2International Maternal Pediatric Adolescent AIDS Clinical Trials Group2Radboud University Medical Center2Adeniyi Olagunju1All India Institute of Medical Sciences1Ann & Robert H Lurie Children's Hospital of Chicago1Centre Hospitalier Universitaire Saint Pierre1CIPRA SA1

Drug identity and terminology: RxNorm. Trial relationships: ClinicalTrials.gov.