Disease & disorder

obsessive-compulsive personality disorder

MONDO:0001158

A disorder characterized by an enduring pattern of inflexibility, extreme orderliness, and perfectionism which interfere with efficiency and which may manifest in many different contexts, including work and leisure activities, financial matters, and issues of morality or ethics.

Clinical trials8
Recruiting2
Drug concepts studied2
Synonyms1

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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Background context

Obsessive–compulsive personality disorder

Obsessive–compulsive personality disorder (OCPD) is a personality disorder marked by a spectrum of obsessions with rules, lists, schedules, and order, among other things. Symptoms are usually present by the time a person reaches adulthood, and are visible in a variety of situations. The cause of OCPD is thought to involve a combination of genetic and environmental factors, namely problems with attachment, but in some individuals there may be a link to brain trauma or Parkinson's disease. Obsessive–compulsive personality disorder is distinct from obsessive–compulsive disorder (OCD), and the relation between the two is contentious. Some studies have found high comorbidity rates between the two disorders but others have shown little comorbidity. Both disorders may share outside similarities, such as rigid and ritual-like behaviors. OCPD is highly comorbid with other personality disorders, autism spectrum, eating disorders, anxiety, mood disorders, and substance use disorders. People with OCPD are seldom conscious of their actions, while people with OCD tend to be aware of how their condition affects the way they act. The disorder is the most common personality disorder in the United States, and is diagnosed twice as often in males than in females; however, there is evidence to suggest the prevalence between men and women is equal.

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

8 shown

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.