Intervention
Psilocybin
ClinicalTrials.gov intervention label
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Search across original and mapped recordsSearch results distinguish clinical terminology from original registry names. Shared trial participation does not imply treatment or approval.
How to interpret these research links
Connected source recordsThis is the original ClinicalTrials.gov intervention label, found in 31 distinct published trials. Registry interventions may represent drugs, devices, procedures or other study activities. A matched term or study association does not establish product equivalence, efficacy or regulatory approval.
Data basis: current published ClinicalTrials.gov records and, where present, RxNorm, MONDO and FDA-label identifiers. See the evidence interpretation and counting methodology.
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Clinical trials
31 shownPsilocybin Intervention for Veterans Overcoming Treatment-Resistant DepressionNCT07226232 · 2026-08-03
RECRUITINGEffect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive DisorderNCT07703722 · 2026-04-01
RECRUITINGPsilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung CancerNCT07216404 · 2026-01-01
RECRUITINGA Randomized Neuroimaging Trial of Psilocybin in DepressionNCT06072898 · 2025-05-28
RECRUITINGPsilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive DisorderNCT06592833 · 2025-02-25
RECRUITINGPsilocybin rTMS for Treatment Resistant DepressionNCT06132178 · 2025-01-10
RECRUITINGStudy of Psilocybin Assisted Psychotherapy to Address Fear of RecurrenceNCT06430541 · 2024-11-21
RECRUITINGOpen-Label Psilocybin Study in Transdiagnostic PopulationNCT06442423 · 2024-10-17
RECRUITINGThe Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive DisorderNCT06247839 · 2024-09-10
RECRUITINGPsilocybin Therapy for Depression in Parkinson's DiseaseNCT06455293 · 2024-08-19
RECRUITINGPsilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's DiseaseNCT04123314 · 2021-03-24
RECRUITINGNeuroplasticity Enhancement From Cognitive Training Reinforced by PsilocybinNCT07721467 · 2026-10-12
NOT_YET_RECRUITINGEffect of Psilocybin Only and Psilocybin Assisted Cognitive Behavioral Therapy in the Management of Major Depressive Disorder and Associated Metabolic, Immune, Inflammatory, Neuroplasticity and Electrical Activity MarkersNCT06746441 · 2024-12-01
COMPLETEDPsilocybin for Major Depressive DisorderNCT05675800 · 2024-01-01
WITHDRAWNPsilocybin in Co-occuring Major Depressive Disorder and Borderline Personality DisorderNCT05399498 · 2023-11-01
COMPLETEDTwo Doses of Psilocybin for the Treatment of MDD in Adults With CancerNCT05947383 · 2023-10-23
ACTIVE_NOT_RECRUITINGPET Synaptogenesis After Psilocybin In DEpression RecoveryNCT05601648 · 2023-07-01
WITHDRAWNPsilocybin-assisted CBT for DepressionNCT05227612 · 2023-06-27
COMPLETEDA Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive DisorderNCT05733546 · 2023-01-30
ACTIVE_NOT_RECRUITINGEffect of SSRIs on Response to Psilocybin TherapyNCT05594667 · 2023-01-01
WITHDRAWNThe Effects of Psilocybin on Self-Focus and Self-Related Processing in Treatment Resistant MDDNCT05381974 · 2022-09-15
WITHDRAWNThe Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal IdeationNCT05220410 · 2022-03-28
COMPLETEDPsilocybin for Treatment-Resistant DepressionNCT05029466 · 2021-11-19
COMPLETEDEfficacy and Safety of Psilocybin in Treatment-Resistant Major DepressionNCT04670081 · 2021-06-10
COMPLETEDPsilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use DisorderNCT04620759 · 2021-04-14
ACTIVE_NOT_RECRUITINGThe Effect of Psilocybin on MDD Symptom Severity and Synaptic DensityNCT04630964 · 2021-01-01
COMPLETEDThe Safety and Efficacy of Psilocybin in Cancer Patients With Major Depressive DisorderNCT04593563 · 2020-09-01
UNKNOWNA Study of Psilocybin for Major Depressive Disorder (MDD)NCT03866174 · 2020-01-23
COMPLETEDPsilocybin and DepressionNCT03380442 · 2018-09-01
UNKNOWNPsilocybin-assisted Group Therapy for Demoralization in Long-term AIDS SurvivorsNCT02950467 · 2018-01-05
COMPLETEDEffects of Psilocybin in Major Depressive DisorderNCT03181529 · 2017-08-10
COMPLETEDCommon conditions
Major Depressive Disorder17Depression6Treatment Resistant Depression3Depressive Disorder2Alcohol Use Disorder1Alzheimer Disease1Alzheimer's Disease1Anhedonia1Anxiety1Borderline Personality Disorder1Breast Cancer1Cancer1Depression - Major Depressive Disorder1Depressive Disorder, Major1Depressive Symptoms1Distress1Grief1Lung Non-Small Cell Carcinoma1Major Depression1MDD1Mild Cognitive Impairment1Mild Depression1Moderate Depression1OCD1Ovarian Cancer1
Mapped diseases appearing in these trials
Shared study participation does not establish that this intervention treats a disease.
Leading sponsors
Johns Hopkins University
3
Khyber Medical University Peshawar
2
Washington University School of Medicine
2
Alan Davis
1
Brain and Cognition Discovery Foundation
1
Central Institute of Mental Health, Mannheim
1
COMPASS Pathways
1
Cybin Therapeutics Inc.
1
Icahn School of Medicine at Mount Sinai
1
Joshua Woolley
1
Joshua Woolley, MD, PhD
1
Maryland Oncology Hematology, PA
1
Massachusetts General Hospital
1
National Institute on Aging (NIA)
1
Section for Affective Disorders; Northern Stockholm Psychiatry
1
Trial status mix
RECRUITING11
COMPLETED10
WITHDRAWN4
ACTIVE_NOT_RECRUITING3
UNKNOWN2
NOT_YET_RECRUITING1
Phase mix
PHASE223
PHASE14
PHASE33
EARLY_PHASE11
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Registry-derived research relationships: ClinicalTrials.gov. Raw condition and intervention labels remain distinct from canonical MONDO/RxNorm entities unless separately normalized.