Disease & disorder

tumor suppressor gene on chromosome 11

MONDO:0011282

Clinical trials82
Recruiting11
Drug concepts studied20
Synonyms4

Disease research snapshot

CureCurrent currently links 82 distinct registered clinical trials to tumor suppressor gene on chromosome 11 through its MONDO disease mappings. 11 of those studies have the registry status “recruiting” (13%). These are registry statuses, not availability guarantees, study results or evidence of effectiveness.

The leading sponsor shown in this linked dataset is Washington University School of Medicine, associated with 9 distinct linked trials. This is a count of records, not a ranking of the sponsor's scientific quality.

The highest-count mapped research city in the current result is St Louis, United States. Only site locations available in the published registry projection are counted; some trial sites may be missing or outdated.

The most frequently mapped drug concept in the current linked trials is cisplatin (4 distinct trials). This describes what has been studied, not a recommended treatment.

Numbers are derived from CureCurrent's current ClinicalTrials.gov projection and conservative MONDO/RxNorm mappings. See sources, counting rules and limitations and verify eligibility or clinical findings with the original study record.

Research intelligence

Directly mapped studies only · unique clinical trials

Current registry observations. Phase counts may overlap. Study start dates are not registry registration dates. Investigational interventions are not approved-treatment recommendations.

Medications under investigation

Verified disease and drug mappings that co-occur within the same study; not evidence of effectiveness.

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MONDO disease family

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Recruiting studies by city

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Trial status

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Trial phase

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Study start year

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Investigated drug interventions

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Background context

tumor suppressor gene on chromosome 11

Background only. Canonical identity remains MONDO; clinical-trial relationships come from ClinicalTrials.gov.

Clinical trials

40 shown
A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid TumorsNCT07636785 · 2026-07-16
RECRUITING
Evaluating the Efficacy and Safety of AI Localization Models in Multidisciplinary Team Care for NSCLCNCT07626736 · 2025-12-01
RECRUITING
Prospective Data Collection Initiative on Thoracic MalignanciesNCT06996249 · 2025-08-15
RECRUITING
Patient-centered, Optimal Integration of Survivorship and Palliative CareNCT04900935 · 2023-09-29
RECRUITING
A Study of HS-10365 in Patients With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung CancerNCT06147570 · 2023-09-25
RECRUITING
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing TumorsNCT05283330 · 2022-12-22
RECRUITING
I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With ImmunotherapyNCT05537922 · 2022-10-01
RECRUITING
Study of PRO in Patients With Advanced Pancreatic or Biliary Tract Cancer (BetterEveryDay)NCT04611867 · 2021-08-17
RECRUITING
Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/ImmunotherapyNCT04253964 · 2020-07-01
RECRUITING
A Multicenter Cancer Biospecimen Collection StudyNCT04510129 · 2020-02-05
RECRUITING
TCR-T Cell Immunotherapy of Lung Cancer and Other Solid TumorsNCT03778814 · 2018-12-01
RECRUITING
XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 MutationNCT05275374 · 2025-12-31
NOT_YET_RECRUITING
Implementation of Lung Cancer Screening in the First Line Zone of ZORA (Flanders), Using a Low Dose CT-scanNCT06293833 · 2024-09-01
UNKNOWN
Study to Investigate Luveltamab Tazevibulin in Adults With Advanced or Metastatic Non-small Cell Lung CancerNCT06555263 · 2024-08-21
WITHDRAWN
A Study to Evaluate the Efficacy of Osimertinib in Patients With EGFR-sensitive Mutated Non-small Cell Lung Cancer Progression After Receiving Adjuvant Targeted Therapy Following Radical SurgeryNCT06530719 · 2024-07-01
NOT_YET_RECRUITING
Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP)NCT06231680 · 2024-01-19
UNKNOWN
Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLCNCT05873439 · 2023-05-25
COMPLETED
Study of Durvalumab + Tremelimumab in NSCLC Patients After Adjuvant TreatmentNCT04625699 · 2022-12-01
WITHDRAWN
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STSNCT05688280 · 2022-11-29
ACTIVE_NOT_RECRUITING
Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationNCT05358249 · 2022-10-24
ACTIVE_NOT_RECRUITING
A Study of [14C]GB491 in Male Healthy SubjectsNCT05860582 · 2022-09-14
COMPLETED
Breathe Easier II: A Dyad-based Multiple Behavior InterventionNCT05956782 · 2022-06-15
COMPLETED
A Study of HMBD-002, a Monoclonal Antibody Targeting VISTA, as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced Solid TumorsNCT05082610 · 2022-02-28
COMPLETED
Analyzing Clinical Outcomes and Genomic Data of American Indian Patient PopulationNCT05863052 · 2022-01-31
ACTIVE_NOT_RECRUITING
Stereotactic Body Radiotherapy for Lung Lesions With Markerless Tracking (MLT) on the VERO® SBRT SystemNCT06722885 · 2022-01-01
WITHDRAWN
NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLCNCT04984811 · 2021-11-15
TERMINATED
This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.NCT05061940 · 2021-05-05
TERMINATED
Trial of NanoPac Intratumoral Injection in Lung CancerNCT04314895 · 2021-04-14
COMPLETED
Cios Mobile 3D Spin for Robotic BronchoscopyNCT04740047 · 2021-02-01
COMPLETED
Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin ToxicityNCT04631731 · 2020-12-15
UNKNOWN
Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated NSCLC PatientsNCT04566432 · 2020-07-01
COMPLETED
Feasibility of Wearable Activity Trackers for Detection of TOXicity in People Receiving Systemic Anticancer TreatmentNCT04440800 · 2020-07-01
UNKNOWN
First-in-Human Study of XMT-1592 in Patients With Ovarian Cancer and NSCLC Likely to Express NaPi2bNCT04396340 · 2020-05-11
TERMINATED
Metabolic and Microbial Profiling of Lung CancerNCT03998189 · 2019-10-11
TERMINATED
Clinical Study of Anlotinib in Maintenance Treatment of Advanced NSCLCNCT03769805 · 2019-06-15
UNKNOWN
Study of Lorlatinib in ROS1 Rearranged NSCLCNCT03612154 · 2019-05-02
UNKNOWN
X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain MetastasesNCT03753685 · 2019-04-12
ACTIVE_NOT_RECRUITING
CT-based Radiomic Signature Can Identify Adenocarcinoma Lung Tumor HistologyNCT03940846 · 2019-03-01
UNKNOWN
A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLCNCT02905591 · 2018-11-16
ACTIVE_NOT_RECRUITING
The Tracking Molecular Evolution for NSCLC (T-MENC) StudyNCT03838588 · 2018-11-06
UNKNOWN

How to interpret this record

CureCurrent links normalized diseases, medicines, registry study labels, sponsors and research sites. A link is not the same as a finding of clinical effectiveness. Our research guides explain how to compare studies, decode RxNorm identities, and avoid over-interpreting site and trial counts. See the published database coverage for mapping completeness.

Disease identity and terminology: MONDO. Trial relationships: ClinicalTrials.gov.